Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979608 | 0.76 | LPAR3 (0.46) | CYP3A4LPAR3LPAR2LPAR1S1PR2 | |
| SCHEMBL11363600 | 0.72 | LPAR3 (0.58) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL812032 | 0.70 | CYP3A4 (0.56) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL7739244 | 0.70 | CYP3A4 (0.56) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL12816073 | 0.70 | CYP3A4 (0.50) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL30595511 | 0.70 | LPAR3 (0.64) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL14775348 | 0.69 | CYP3A4 (0.45) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL18826143 | 0.69 | MEN1 (0.54) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL17626526 | 0.69 | CYP3A4 (0.54) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL3961974 | 0.69 | CYP3A4 (0.54) | CYP3A4LPAR3LPAR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778699-A4 | TARGETING CHELANTS AND CHELATES | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1778699-A2 | TARGETING CHELANTS AND CHELATES | Dow Gloval Technologies Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020779-A2 | TARGETING CHELANTS AND CHELATES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-02-23 | — | — | WO | disclosed |