SCHEMBL3845447

SCHEMBL3845447

C=Cc1cc(C=C)cc(C23CC4CC(c5cc(C=C)cc(C=C)c5)(C2)CC(C25CC6CC(CC(C6)C2)C5)(C4)C3)c1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
GFER P55789 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3842435 0.94
SCHEMBL3840947 0.93 GRIN2D (0.36) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3849547 0.91
SCHEMBL2763547 0.86 GRIN2D (0.39) GAAMEN1POLBGFERKMT2A
SCHEMBL3848155 0.85 GRIN2D (0.36) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL3841900 0.82 MEN1 (0.30) GAAMEN1POLBGFERKMT2A
SCHEMBL3841898 0.82 MEN1 (0.30) GAAMEN1POLBGFERKMT2A
SCHEMBL3843502 0.80 GRIN2D (0.39) GAAMEN1POLBGFERKMT2A
SCHEMBL3843500 0.80 GRIN2D (0.39) GAAMEN1POLBGFERKMT2A
SCHEMBL2762850 0.80 GRIN2D (0.46) GAAMEN1POLBGFERKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed