Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 1.00 |
| ▸ | FNTB | P49356 | 19/20 | 1.00 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.73 |
| ▸ | NRAS | P01111 | 1/20 | 0.43 |
| ▸ | HRAS | P01112 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855591 | 0.88 | FNTA (1.00) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL445625 | 0.85 | FNTA (1.00) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL445627 | 0.85 | FNTA (1.00) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL31472029 | 0.85 | FNTA (1.00) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL14370795 | 0.80 | FNTA (0.78) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL445940 | 0.80 | FNTA (0.88) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL445938 | 0.80 | FNTA (0.88) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL9082833 | 0.79 | FNTA (0.84) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL9082830 | 0.79 | FNTA (0.84) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL9083210 | 0.79 | FNTA (0.87) | FNTAFNTBPGGT1BNRASHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427418-B1 | PIPERAZINONE COMPOUNDS AS ANTI-TUMOR AND ANTI-CANCER AGENTS | UNIV YALE (US) | 2009-11-11 | — | — | EP | disclosed |