Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.59 |
| ▸ | FNTB | P49356 | 10/20 | 0.59 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7818562 | 0.87 | FNTA (0.54) | FNTAFNTBPGGT1BCYP19A1GRM2 | |
| Hydrochloric Acid SCHEMBL7837910 | 0.87 | FNTA (0.58) | FNTAFNTBPGGT1BCYP19A1GRM2 | |
| SCHEMBL3517007 | 0.85 | FNTA (0.50) | FNTAFNTBPGGT1BCYP19A1ADRA2A | |
| SCHEMBL445626 | 0.85 | FNTA (0.59) | FNTAFNTBPGGT1BCYP19A1GRM2 | |
| SCHEMBL3687066 | 0.85 | FNTA (0.59) | FNTAFNTBPGGT1BCYP19A1GRM2 | |
| Trifluoroacetic Acid SCHEMBL8147178 | 0.80 | FNTA (0.54) | FNTAFNTBPGGT1BCYP19A1 | |
| SCHEMBL445939 | 0.80 | FNTA (0.51) | FNTAFNTBPGGT1BCYP19A1GRM2 | |
| SCHEMBL5131468 | 0.80 | FNTA (0.51) | FNTAFNTBPGGT1BCYP19A1GRM2 | |
| Hydrochloric Acid SCHEMBL8160943 | 0.80 | FNTA (0.51) | FNTAFNTBPGGT1BCYP19A1GRM2 | |
| Hydrochloric Acid SCHEMBL8541088 | 0.80 | FNTA (0.51) | FNTAFNTBPGGT1BCYP19A1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427418-B1 | PIPERAZINONE COMPOUNDS AS ANTI-TUMOR AND ANTI-CANCER AGENTS | UNIV YALE (US) | 2009-11-11 | — | — | EP | disclosed |