Tert-Butanol

Tert-Butanol

SCHEMBL384629

CC(C)(C)[OH2+].F[B-](F)(F)F

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15955554 0.78
Chloromethane SCHEMBL23414945 0.76 TSHR (0.30)
Methyl Alcohol SCHEMBL1528050 0.76
Tert-Butylamine SCHEMBL16966574 0.74 TSHR (0.33)
SCHEMBL25277060 0.74
SCHEMBL15956010 0.74
SCHEMBL534110 0.74
SCHEMBL25276824 0.74
SCHEMBL322573 0.74
SCHEMBL97708 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148443-B2 Oxonium and sulfonium salts MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-04-03 US disclosed
US-8101749-B2 Process for the preparation of onium salts with a tetrafluoroborate anion having a reduced halide content MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-01-24 US disclosed
US-20110034698-A1 Oxonium And Sulfonium Salts IGNATYEV NIKOLAI MYKOLA 2011-02-10 US disclosed
US-7842804-B2 Ionic salts comprising pyrrolidinium, triazolinium, piperidinium or morpholinium cations and alkyltrifluorophosphate anions MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-11-30 US disclosed
US-20090253912-A1 PROCESS FOR THE PREPARATION OF ONIUM SALTS WITH A TETRAFLUOROBORATE ANION HAVING A REDUCED HALIDE CONTENT MERCK PATENT GMBH (DE) 2009-10-08 US disclosed
US-20090036628-A1 OXONIUM AND SULFONIUM SALTS MERCK PATENT GESELLSCHAFT (DE) 2009-02-05 US disclosed