Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 16/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 14/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 14/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 13/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 13/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 13/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.45 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846809 | 1.00 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC8HDAC2 | |
| SCHEMBL3137574 | 0.88 | HDAC1 (0.57) | HDAC1HDAC6HDAC3HDAC8HDAC2 | |
| SCHEMBL3137563 | 0.88 | HDAC1 (0.57) | HDAC1HDAC6HDAC3HDAC8HDAC2 | |
| SCHEMBL28770061 | 0.82 | HDAC1 (0.38) | HDAC1HDAC6HDAC3HDAC8HDAC2 | |
| SCHEMBL296489 | 0.81 | HDAC1 (0.65) | HDAC1HDAC6HDAC3HDAC8HDAC2 | |
| SCHEMBL296490 | 0.81 | HDAC1 (0.65) | HDAC1HDAC6HDAC3HDAC8HDAC2 | |
| SCHEMBL296547 | 0.80 | HDAC1 (0.55) | HDAC1HDAC6HDAC3HDAC8HDAC2 | |
| SCHEMBL296548 | 0.80 | HDAC1 (0.55) | HDAC1HDAC6HDAC3HDAC8HDAC2 | |
| SCHEMBL3140370 | 0.80 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC8HDAC2 | |
| SCHEMBL3140357 | 0.80 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861365-B1 | N-SULPHONYLPYRROLES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2009-07-01 | — | — | EP | claimed |