Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 20/20 | 0.83 |
| ▸ | CPT1B | Q92523 | 19/20 | 0.83 |
| ▸ | CPT2 | P23786 | 9/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905161 | 0.92 | CPT1A (0.84) | CPT1ACPT1BCPT2 | |
| SCHEMBL2900981 | 0.91 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL3847033 | 0.89 | CPT1A (0.95) | CPT1ACPT1BCPT2 | |
| SCHEMBL3577008 | 0.86 | CPT1A (0.82) | CPT1ACPT1BCPT2 | |
| SCHEMBL3566827 | 0.86 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL30015594 | 0.86 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL3844841 | 0.84 | CPT1A (0.84) | CPT1ACPT1BCPT2 | |
| SCHEMBL3569787 | 0.83 | CPT1A (0.73) | CPT1ACPT1BCPT2 | |
| SCHEMBL3575720 | 0.82 | CPT1A (0.83) | CPT1ACPT1BCPT2 | |
| SCHEMBL3578510 | 0.82 | CPT1A (1.00) | CPT1ACPT1BCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097373-A1 | SULFONAMIDE DERIVATIVES AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTL ) | F. Hoffmann-Roche AG (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008074692-A1 | SULFONAMIDE DERIVATIVES AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTL ) | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | WO | disclosed |