Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285811 | 0.74 | AKR1B1 (0.74) | GAAKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29570152 | 0.74 | AKR1B1 (0.74) | GAAKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL13873152 | 0.74 | KMT2A (0.44) | GAAKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3935646 | 0.73 | KMT2A (0.58) | GAAKMT2AMAPTLMNAKDM4E | |
| SCHEMBL13873165 | 0.72 | MAPK1 (0.40) | GAAKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL5254398 | 0.72 | KDM4E (0.56) | GAAKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6362585 | 0.72 | TDP1 (0.57) | GAAKMT2AMAPTLMNAKDM4E | |
| SCHEMBL1885453 | 0.71 | MAPT (0.59) | GAAKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL14814503 | 0.70 | SMN1; SMN2 (0.56) | GAAKMT2AMAPTLMNAKDM4E | |
| SCHEMBL7639203 | 0.70 | KMT2A (0.50) | KMT2AMAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |