SCHEMBL3847161

SCHEMBL3847161

[CH2]CC1CCNC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28049436 0.86
SCHEMBL27479234 0.82
SCHEMBL8370882 0.80 KDM4E (0.34)
SCHEMBL25766083 0.78
SCHEMBL3330457 0.76
SCHEMBL4409894 0.76
SCHEMBL30497363 0.76
SCHEMBL8224717 0.76
SCHEMBL1271144 0.76
SCHEMBL6606480 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108779114-A naphthyridine compounds as integrin antagonists 葛兰素史密斯克莱知识产权发展有限公司 2018-11-09 CN disclosed
CN-1679595-B Phosphonocephem derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES LTD 2010-05-12 CN disclosed
EP-2080765-A1 Phosphonocephem Derivates, Their Production And Use Takeda Pharmaceutical Company Limited (JP) 2009-07-22 EP disclosed
EP-1043327-B1 PHOSPHONOCEPHEM DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME, AND USE THEREOF TAKEDA PHARMACEUTICAL (JP) 2009-04-29 EP disclosed
CN-1835945-A Chinazoline derivatives as aurora kinase inhibitors ASTRAZENECA AB (SE) 2006-09-20 CN disclosed
US-20060178382-A1 Chinazoline derivatives as aurora kinase inhibitors ASTRAZENECA AB (SE) 2006-08-10 US disclosed
CN-1679595-A Phosphonocephem derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2005-10-12 CN disclosed
CN-1194980-C Phosphonocephem derivatives, their preparation and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2005-03-30 CN disclosed
CN-1436204-A Magnetic or magnetisable bonding agent composition EMTEC MAGNETICS GMBH (DE) 2003-08-13 CN disclosed
CN-1436198-A Method for production of polymerisation reaction product BASF AG (DE) 2003-08-13 CN disclosed
EP-0216385-A2 Antibacterial compounds Takeda Chemical Industries, Ltd. (JP) 1987-04-01 EP disclosed
CN-85105977-A The preparation method of antimicrobial compounds 1987-02-25 CN disclosed
CN-86102034-A Process for the production of antibacterial compounds 1987-01-07 CN disclosed
EP-0203271-A2 Antibacterial compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1986-12-03 EP disclosed
CN-85105988-A The preparation method of cephem compounds 1986-10-29 CN disclosed
WO-1986005183-A1 ANTIBACTERIAL COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-09-12 WO disclosed
EP-0164113-A2 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1985-12-11 EP disclosed
EP-0164122-A2 Cephem compounds Takeda Chemical Industries, Ltd. (JP) 1985-12-11 EP disclosed
EP-0160252-A2 Antibacterial compounds Takeda Chemical Industries, Ltd. (JP) 1985-11-06 EP disclosed
US-4234482-A Substituted 3-carbalkoxy 4-alkylamino-azobenzene compound as disperse dyestuffs for synthetic fibers PRODUITS CHIMIQUES UGINE KUHLMANN SERVICE PROPRIETE INDUSTRIELLE (FR) 1980-11-18 US disclosed