Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616622 | 0.82 | MAPT (0.53) | MAPTKMT2AEPHX1CYP2D6CYP1A2 | |
| SCHEMBL4560696 | 0.82 | MAPT (0.53) | MAPTKMT2AEPHX1CYP2D6CYP1A2 | |
| SCHEMBL616401 | 0.81 | MAPT (0.52) | MAPTKMT2AEPHX1CYP2D6CYP1A2 | |
| SCHEMBL615873 | 0.81 | KMT2A (0.52) | MAPTKMT2AEPHX1CYP2D6CYP1A2 | |
| SCHEMBL5053650 | 0.79 | MAPT (0.59) | MAPTKMT2ACYP2D6CYP1A2KCNN4 | |
| SCHEMBL2416799 | 0.79 | ATM (0.59) | MAPTKMT2AATML3MBTL1EPHX1 | |
| SCHEMBL616297 | 0.78 | MAPT (0.49) | MAPTKMT2AATMEPHX1CYP2D6 | |
| SCHEMBL4559945 | 0.78 | MAPT (0.49) | MAPTKMT2AEPHX1CYP2D6CNR1 | |
| SCHEMBL618739 | 0.78 | KMT2A (0.49) | MAPTKMT2AATML3MBTL1EPHX1 | |
| SCHEMBL22758072 | 0.77 | ATM (0.49) | MAPTKMT2AATML3MBTL1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101747455-B | Supported main catalyst for olefin polymerization and preparation method thereof | PETROCHINA CO LTD | 2012-03-07 | — | — | CN | claimed |
| CN-101747456-B | Polypropylene catalyst and preparation method thereof | PETROCHINA CO LTD | 2012-03-07 | — | — | CN | claimed |
| CN-101747456-A | Polypropylene catalyst and preparation method thereof | PETROCHINA CO LTD | 2010-06-23 | — | — | CN | claimed |
| CN-101747455-A | Supported main catalyst for olefin polymerization and preparation method thereof | PETROCHINA CO LTD | 2010-06-23 | — | — | CN | claimed |
| CN-101747456-A | Polypropylene catalyst and preparation method thereof | PETROCHINA CO LTD | 2010-06-23 | — | — | CN | disclosed |
| CN-101747455-A | Supported main catalyst for olefin polymerization and preparation method thereof | PETROCHINA CO LTD | 2010-06-23 | — | — | CN | disclosed |
| EP-2099815-A2 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | Acure Pharma AB (SE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008058679-A2 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ACURE PHARMA AB (SE) | 2008-05-22 | — | — | WO | disclosed |