Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.81 |
| ▸ | PPARG | P37231 | 11/20 | 0.81 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.54 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17274732 | 1.00 | PPARA (0.81) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL2434760 | 0.94 | PPARG (0.76) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL10625909 | 0.89 | PPARA (1.00) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL18803105 | 0.89 | PPARA (1.00) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL3840661 | 0.89 | PPARG (0.71) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL10628752 | 0.88 | PPARA (0.97) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL10625874 | 0.88 | PPARA (0.97) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL17274681 | 0.88 | PPARA (0.79) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL18803106 | 0.87 | PPARA (0.77) | PPARAPPARGCYP4F2CYP4A11PPARD | |
| SCHEMBL2439451 | 0.85 | PPARA (0.74) | PPARAPPARGCYP4F2CYP4A11PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |