Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851794 | 0.95 | DYRK1A (0.33) | MAPTRAB9ADYRK1A | |
| SCHEMBL3848976 | 0.86 | FGFR1 (0.39) | FGFR1MAPTRAB9ADYRK1A | |
| SCHEMBL3849700 | 0.85 | DYRK1A (0.33) | MAPTRAB9ADYRK1A | |
| SCHEMBL3855975 | 0.85 | DYRK1A (0.33) | MAPTRAB9ADYRK1A | |
| SCHEMBL3847150 | 0.81 | FGFR1 (0.33) | FGFR1MAPTRAB9ADYRK1A | |
| SCHEMBL3851788 | 0.80 | DYRK1A (0.39) | FGFR1MAPTRAB9ADYRK1A | |
| SCHEMBL3847279 | 0.78 | CCR3 (0.36) | MAPTRAB9A | |
| SCHEMBL3850669 | 0.75 | AKT1 (0.31) | — | |
| SCHEMBL3846716 | 0.72 | POLB (0.33) | — | |
| SCHEMBL3849620 | 0.72 | MAPK14 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048142-A2 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | Eisai R&D Management Co., Ltd. (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-1382603-B1 | NITROGENOUS FUSED-RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | EISAI R&D MAN CO LTD (JP) | 2008-07-23 | — | — | EP | disclosed |
| EP-1382603-A1 | NITROGENOUS FUSED−RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | Eisai Co., Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |