SCHEMBL3849115

SCHEMBL3849115

O=c1[nH]c2c(-c3ccc(-c4cccc5oc(=O)[nH]c45)cc3)cccc2o1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.47
OGT O15294 1/20 0.47
GRM5 P41594 13/20 0.45
EPHX2 P34913 3/20 0.42
PDE3B Q13370 2/20 0.37
PDE3A Q14432 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17260667 0.93 GRM5 (0.50) MCL1OGTGRM5EPHX2
SCHEMBL3854410 0.89 MCL1 (0.45) MCL1OGTGRM5EPHX2
SCHEMBL31686101 0.74 MCL1 (0.49) MCL1OGTGRM5EPHX2
SCHEMBL5077255 0.74 PSMB8 (0.61) MCL1OGTGRM5EPHX2
SCHEMBL30146353 0.74 PSMB8 (0.61) MCL1OGTGRM5EPHX2
SCHEMBL3043379 0.74 MCL1 (0.49) MCL1OGTGRM5EPHX2
SCHEMBL1285749 0.74 EPHX2 (0.50) MCL1OGTGRM5EPHX2
SCHEMBL2484702 0.74 MCL1 (0.49) MCL1OGTGRM5EPHX2
SCHEMBL5540274 0.74 MCL1 (0.49) MCL1OGTGRM5EPHX2
SCHEMBL1137634 0.74 PSMB8 (0.61) MCL1OGTGRM5EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090316084-A1 Method of Producing Polarizing Plate, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2009-12-24 US disclosed
US-20090286098-A1 Optical Film, Method of Producing the Same and Image Displaying Apparatus Employing the Optical Film KONICA MINOLTA OPTO, INC. (JP) 2009-11-19 US disclosed