Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21817071 | 0.90 | NR5A1 (0.55) | PTPN11LMNAALDH1A1MAPTNR5A1 | |
| SCHEMBL3120916 | 0.90 | NR5A1 (0.55) | PTPN11LMNAALDH1A1MAPTNR5A1 | |
| SCHEMBL29801834 | 0.90 | NR5A1 (0.55) | PTPN11LMNAALDH1A1MAPTNR5A1 | |
| SCHEMBL31298797 | 0.90 | NR5A1 (0.55) | PTPN11LMNAALDH1A1MAPTNR5A1 | |
| SCHEMBL31298880 | 0.90 | NR5A1 (0.55) | PTPN11LMNAALDH1A1MAPTNR5A1 | |
| SCHEMBL6711621 | 0.90 | NR5A1 (0.55) | PTPN11LMNAALDH1A1MAPTNR5A1 | |
| SCHEMBL29973596 | 0.90 | NR5A1 (0.55) | PTPN11LMNAALDH1A1MAPTNR5A1 | |
| SCHEMBL28520504 | 0.90 | NR5A1 (0.49) | PTPN11LMNAALDH1A1MAPTHTT | |
| Biphenyl SCHEMBL27847771 | 0.88 | PTPN11 (0.52) | PTPN11NR5A1PDK2MEN1KMT2A | |
| SCHEMBL77484 | 0.86 | NR5A1 (0.60) | PTPN11ALDH1A1MAPTNR5A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814937-B1 | ANTIMICROBIAL POLYMER COMPOSITIONS HAVING IMPROVED DISCOLORATION RESISTANCE | CIBA HOLDING INC (CH) | 2009-07-29 | — | — | EP | claimed |