Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060209 | 0.88 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28472133 | 0.79 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5057282 | 0.79 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acetic Acid SCHEMBL3361156 | 0.78 | TSHR (0.70) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL13101258 | 0.77 | — | — | |
| SCHEMBL27856672 | 0.76 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29550542 | 0.76 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL34661 | 0.76 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9103359 | 0.76 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid SCHEMBL30787943 | 0.76 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922883-B1 | POLYMER AND ITS PREPARATION AND USE | KEMIRA OYJ (FI) | 2017-11-15 | — | — | EP | claimed |
| EP-1773905-B1 | HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM | LUBRIZOL ADVANCED MAT INC (US) | 2013-10-09 | — | — | EP | claimed |
| EP-1784435-B1 | METHODS FOR PRODUCING CROSSLINKABLE OLIGOMERS | NUPLEX RESINS BV (NL) | 2009-11-11 | — | — | EP | claimed |