⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18561492 | 0.86 | — | — | |
| SCHEMBL3854100 | 0.86 | — | — | |
| SCHEMBL15291893 | 0.78 | HRH4 (0.42) | — | |
| SCHEMBL15291894 | 0.77 | AKT1 (0.41) | — | |
| SCHEMBL15291880 | 0.77 | JAK2 (0.37) | — | |
| SCHEMBL5145189 | 0.74 | MAP4K4 (0.39) | — | |
| SCHEMBL14018247 | 0.74 | HRH4 (0.47) | — | |
| SCHEMBL9974697 | 0.71 | MAPT (0.37) | — | |
| SCHEMBL3856669 | 0.70 | SLC18A3 (0.31) | — | |
| SCHEMBL2265811 | 0.70 | RAD52 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | claimed |
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | claimed |
| EP-2155153-B1 | DYEING COMPOSITION COMPRISING A SPECIFIC AMINOPYRAZOLOPYRIDINE OXIDATION BASE, A COUPLER AND A SPECIFIC SURFACTANT | L'ORÉAL (FR) | 2017-03-01 | — | — | EP | claimed |
| EP-2651935-B1 | DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER | ORÉAL L (FR) | 2016-11-23 | — | — | EP | claimed |
| US-7578856-B2 | Dyeing compositions comprising at least one aminopyrazolopyridine oxidation base, at least one coupler and at least one C4-C30 polyol and methods and use thereof | L'OREAL S.A. (FR) | 2009-08-25 | — | — | US | claimed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | claimed |
| EP-1992329-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base and a specific associative polymer | L'Oréal (FR) | 2008-11-19 | — | — | EP | claimed |
| US-11730688-B2 | Composition for dyeing the hair, comprising a heterocyclic oxidation base and a 2-amino-5-ethylphenol coupler | L'OREAL (FR) | 2023-08-22 | — | — | US | disclosed |
| US-10568821-B2 | Dye composition comprising a para-phenylenediamine oxidation base and a heterocyclic oxidation base | L'OREAL (FR) | 2020-02-25 | — | — | US | disclosed |
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | disclosed |
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | disclosed |
| US-20170354580-A1 | DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE | L'OREAL (FR) | 2017-12-14 | — | — | US | disclosed |
| WO-2017108847-A1 | COMPOSITION FOR DYEING THE HAIR, COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 2-AMINO-5-ETHYLPHENOL COUPLER | L'OREAL (FR) | 2017-06-29 | — | — | WO | disclosed |
| WO-2008138844-A1 | DYEING COMPOSITION COMPRISING A SPECIFIC AMINOPYRAZOLOPYRIDINE OXIDATION BASE, A COUPLER AND A SPECIFIC SURFACTANT | L'OREAL (FR) | 2008-11-20 | — | — | WO | disclosed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992330-A2 | Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992329-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base and a specific associative polymer | L'Oréal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992329-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base and a specific associative polymer | L'Oréal (FR) | 2008-11-19 | — | — | EP | disclosed |
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'OREAL S.A. (FR) | 2007-06-21 | — | — | US | disclosed |
| EP-1792903-A1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | L'OREAL (FR) | 2007-06-06 | — | — | EP | disclosed |