⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19703051 | 0.90 | — | — | |
| SCHEMBL27108245 | 0.90 | — | — | |
| SCHEMBL19241756 | 0.90 | — | — | |
| SCHEMBL8395064 | 0.86 | — | — | |
| SCHEMBL22185231 | 0.86 | — | — | |
| SCHEMBL8271701 | 0.86 | — | — | |
| SCHEMBL23551103 | 0.85 | — | — | |
| SCHEMBL1842412 | 0.83 | — | — | |
| SCHEMBL12948970 | 0.83 | — | — | |
| SCHEMBL24324448 | 0.81 | CYP2D6 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017189661-A1 | 6-AMINOPYRIDIN-3-YL THIAZOLES AS MODULATORS OF RORγT | JANSSEN PHARMACEUTICA NV (BE) | 2017-11-02 | — | — | WO | disclosed |
| EP-2678315-B1 | (Pyridin-4-yl)benzylamides as allosteric modulators of alpha 7 nAChR | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-16 | — | — | EP | disclosed |
| EP-2889289-A1 | Pyridazine-dione N-substituted glycine derivatives as HIF hydroxylase inhibitors | GlaxoSmithKline LLC (US) | 2015-07-01 | — | — | EP | disclosed |
| US-8985173-B2 | Manufacturing method and manufacturing apparatus of semiconductor substrate | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-03-24 | — | — | US | disclosed |
| US-RE44613-E1 | N-substituted glycine derivatives: hydroxylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2013-11-26 | — | — | US | disclosed |
| WO-2013112751-A1 | POTENT NON-UREA INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2013-08-01 | — | — | WO | disclosed |
| US-20130177530-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| WO-2012125661-A1 | SUBSTITUTED 3-AZABICYCLO[3.1.0]HEXANE DERIVATIVES USEFUL AS CCR2 ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2012-09-20 | — | — | WO | disclosed |
| CN-102161673-A | Belta-halo ring propyl silane derivative | XIANGGUO LIU | 2011-08-24 | — | — | CN | disclosed |
| US-20100300862-A1 | Touch Panel | SEMICONDUCTOR ENERGY LABORATORIES, CO., LTD. | 2010-12-02 | — | — | US | disclosed |
| US-20040023955-A1 | Tricyclic-2-pyridone compounds useful as HIV reverse transcriptase inhibitors | RODGERS JAMES D (US) | 2004-02-05 | — | — | US | disclosed |
| US-6596729-B2 | Especially in combination with one or more HIV reverse transcriptase inhibitors, HIV protease inhibitors, fusion inhibitors, and/or CCR-5 | BRISTOL-MYERS SQUIBB COMPANY | 2003-07-22 | — | — | US | disclosed |
| EP-1303515-A2 | TRICYCLIC 2-PYRIDONE COMPOUNDS USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-04-23 | — | — | EP | disclosed |
| US-20020107261-A1 | Tricyclic-2-pyridone compounds useful as HIV reverse transcriptase inhibitors | DUPONT PHARMACEUTICALS COMPANY | 2002-08-08 | — | — | US | disclosed |
| WO-2002008226-A2 | TRICYCLIC 2-PYRIDONE COMPOUNDS USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-31 | — | — | WO | disclosed |
| CN-1017900-B | PROCESS FOR PRODUCTION OF ELLIPTICINE DERIVATIVE | SUNTORY LTD (JP) | 1992-08-19 | — | — | CN | disclosed |
| EP-0173462-B1 | ELLIPTICINE DERIVATIVE AND PRODUCTION PROCESS THEREOF | SUNTORY LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |
| US-4698423-A | ANTITUMOR AGENTS | SUNTORY LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |
| CN-85107911-A | The production method of ellipticine derivative | — | 1987-02-25 | — | — | CN | disclosed |
| EP-0173462-A2 | Ellipticine derivative and production process thereof | SUNTORY LIMITED (JP) | 1986-03-05 | — | — | EP | disclosed |