SCHEMBL3852142

SCHEMBL3852142

O=C1NC(=O)c2c(Br)ccc3cccc1c23

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 4/20 0.63
NPSR1 Q6W5P4 2/20 0.54
CYP1B1 Q16678 1/20 0.50
ALDH1A1 P00352 2/20 0.44
CES1 P23141 2/20 0.44
CES2 O00748 1/20 0.44
BCHE P06276 1/20 0.44
MCL1 Q07820 1/20 0.44
GSK3B P49841 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 2/20 0.41
CASP7 P55210 2/20 0.41
RGS12 O14924 1/20 0.41
USP2 O75604 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CYP3A4 P08684 1/20 0.41
THRB P10828 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29089233 0.81 PARP1 (0.66) PARP1NPSR1ALDH1A1CES1CES2
SCHEMBL3850862 0.80 NPSR1 (0.59) PARP1NPSR1CYP1B1ALDH1A1CES1
SCHEMBL28935123 0.79 PARP1 (0.63) PARP1NPSR1ALDH1A1CES1CES2
SCHEMBL21450709 0.79 PARP1 (0.63) PARP1NPSR1ALDH1A1CES1CES2
SCHEMBL6848270 0.79 PARP1 (0.63) PARP1NPSR1ALDH1A1CES1CES2
SCHEMBL1756367 0.79 PARP1 (0.63) PARP1NPSR1ALDH1A1CES1CES2
SCHEMBL29053384 0.79 PARP1 (0.63) PARP1NPSR1ALDH1A1CES1CES2
SCHEMBL339347 0.79 PARP1 (0.63) PARP1NPSR1ALDH1A1CES1CES2
Pyrene SCHEMBL28900225 0.79 PARP1 (0.91) PARP1NPSR1CYP1B1ALDH1A1CES1
SCHEMBL2487811 0.79 PARP1 (1.00) PARP1NPSR1ALDH1A1CES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116162061-A Naphthalimide derivative fluorescent probe containing aldehyde group and preparation method and application thereof 上海应用技术大学 2023-05-26 CN claimed
CN-113088278-B Room-temperature phosphorescent material and preparation method thereof 华东理工大学 2022-10-21 CN claimed
CN-113150575-B Near-infrared naphthalimide dye and preparation method and application thereof 福州大学 2022-10-04 CN claimed
CN-110845495-B Synthesis method of triplet photosensitizer 齐齐哈尔大学 2022-01-18 CN claimed
CN-113150575-A Near-infrared naphthalimide dye and preparation method and application thereof 福州大学 2021-07-23 CN claimed
CN-110845495-A Triplet photosensitizers and methods of synthesis 齐齐哈尔大学 2020-02-28 CN claimed
US-20070270570-A1 WHITE ELECTROLUMINESCENT POLYMERIC MATERIAL AND PREPARATION THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINES ACADEMY OF SCIENCE (CN) 2007-11-22 US claimed
US-20050214568-A1 White electroluminescent polymeric material & preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE 2005-09-29 US claimed
CN-116162061-B Naphthalimide derivative fluorescent probe containing aldehyde group and preparation method and application thereof 上海应用技术大学 2024-06-28 CN disclosed
CN-116162061-B Naphthalimide derivative fluorescent probe containing aldehyde group and preparation method and application thereof 上海应用技术大学 2024-06-28 CN disclosed
CN-117924339-A Hydrogen sulfide donor and preparation method and application thereof 重庆理工大学 2024-04-26 CN disclosed
WO-2023135609-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT SOLVENT-FREE ORGANIC LIQUID COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2023-07-20 WO disclosed
CN-116162061-A Naphthalimide derivative fluorescent probe containing aldehyde group and preparation method and application thereof 上海应用技术大学 2023-05-26 CN disclosed
CN-116162061-A Naphthalimide derivative fluorescent probe containing aldehyde group and preparation method and application thereof 上海应用技术大学 2023-05-26 CN disclosed
CN-110283266-B Pure organic room temperature phosphorescent polymer material with lactam ring structure and preparation method thereof 华东理工大学 2020-12-04 CN disclosed
CN-110845495-A Triplet photosensitizers and methods of synthesis 齐齐哈尔大学 2020-02-28 CN disclosed
US-7579091-B2 White electroluminescent polymeric material and preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) 2009-08-25 US disclosed
US-20070270570-A1 WHITE ELECTROLUMINESCENT POLYMERIC MATERIAL AND PREPARATION THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINES ACADEMY OF SCIENCE (CN) 2007-11-22 US disclosed
US-20050214568-A1 White electroluminescent polymeric material & preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE 2005-09-29 US disclosed
US-3932413-A Process for the preparation of 4'-alkoxy-4-naphthalimido-pyrazolium compounds and intermediates therefor PRODUCTS CHIMIQUES UGINE KUHLMANN (FR) 1976-01-13 US disclosed