Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 20/20 | 0.67 |
| ▸ | NR1H3 | Q13133 | 20/20 | 0.67 |
| ▸ | PPARG | P37231 | 3/20 | 0.67 |
| ▸ | PPARD | Q03181 | 1/20 | 0.67 |
| ▸ | PPARA | Q07869 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124999 | 0.89 | NR1H2 (0.65) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL3848816 | 0.86 | NR1H2 (0.69) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL3851959 | 0.86 | NR1H2 (0.68) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124852 | 0.85 | NR1H2 (0.67) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124565 | 0.84 | NR1H2 (0.79) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4259187 | 0.83 | NR1H2 (0.70) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1126623 | 0.83 | NR1H2 (0.77) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124760 | 0.83 | NR1H2 (0.64) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4261618 | 0.82 | NR1H2 (0.71) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124816 | 0.82 | NR1H2 (0.76) | NR1H2NR1H3PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576215-B2 | Quinolines and pharmaceutical compositions thereof | WYETH (US) | 2009-08-18 | — | — | US | claimed |