Ipratropium

Ipratropium

SCHEMBL3854

CC(C)[N@@+]1(C)[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2.[Br-]

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM3

The experimentally established mechanism targets of Ipratropium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 known ✓ P20309 5/20 0.98
CHRM2 P08172 7/20 0.98
CHRM5 P08912 6/20 0.98
CHRM1 P11229 5/20 0.98
CHRM4 P08173 4/20 0.98
MEN1 O00255 3/20 0.98
KMT2A Q03164 3/20 0.98
SMN1; SMN2 Q16637 2/20 0.98
TSHR P16473 2/20 0.98
BLM P54132 5/20 0.80
PABPC1 P11940 1/20 0.77
CYP2C19 P33261 1/20 0.75
CYP3A4 P08684 1/20 0.64
CYP2C9 P11712 1/20 0.64
HIF1A Q16665 1/20 0.64
HSD17B10 Q99714 1/20 0.64
KDM4E B2RXH2 1/20 0.62
LMNA P02545 1/20 0.62
POLB P06746 1/20 0.62
ADRA2C P18825 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ipratropium SCHEMBL16762661 1.00 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL3853 1.00 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL6854301 1.00 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL107906 1.00 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL30987857 1.00 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL6854302 1.00 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL3852 1.00 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL3299299 0.99 CHRM2 (0.96) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL22077027 0.99 CHRM2 (1.00) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL6553361 0.99 CHRM2 (0.96) CHRM2CHRM5CHRM1CHRM3CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 26793 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423298-B1 None US claimed
WO-2026099512-A1 MEDICAMENT DISPENSER DEVICE PORTAL MEDICAL LIMITED (GB) 2026-05-15 WO claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
US-12616803-B2 Apparatus for dispensing inhalant medicament METOPI PHARMACEUTICALS, INC. (US) 2026-05-05 US claimed
US-20260115161-A1 2-HYDROXY-OCTADECENE-9-CIS-OATE FOR USE IN THE TREATMENT OF ONCOLOGICAL PATHOLOGIES AND NEUROPATHIC PAIN LAMINAR PHARMACEUTICALS S A (ES) 2026-04-30 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-20260077140-A1 METERED DOSE INHALER FOR IPRATROPIUM BROMIDE SOLUTION GLENMARK PHARMACEUTICALS LTD (IN) 2026-03-19 US claimed
US-20260076900-A1 IPRATROPIUM DELIVERY COMPOSITIONS, DEVICES AND METHODS SOLSTICE ADVANCED MATERIALS US, INC. (US) 2026-03-19 US claimed
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
WO-1992000107-A1 AEROSOL DRUG FORMULATIONS GLAXO INC. (US) 1992-01-09 WO claimed
WO-1992000062-A1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-09 WO claimed
EP-0294940-B1 PHARMACEUTICAL COMPOSITIONS FISONS plc (GB) 1991-12-11 EP claimed
US-5049389-A Non-phospholipd lipid, delivery by inhalation LIPOSOME TECHNOLOGY, INC. (US) 1991-09-17 US claimed
WO-1991011173-A1 PROPELLANT COMPOSITIONS FISONS PLC (GB) 1991-08-08 WO claimed
EP-0239798-B1 NEW PHARMACEUTICAL COMPOSITIONS FOR INHALATION CHIESI FARMACEUTICI S.p.A. (IT) 1990-09-26 EP claimed
WO-1990006775-A1 A NOVEL NONPHOSPHOLIPID LIPOSOME COMPOSITION FOR SUSTAINED RELEASE OF DRUGS LIPOSOME TECHNOLOGY, INC. (US) 1990-06-28 WO claimed
EP-0372777-A2 Medicinal aerosol formulations RIKER LABORATORIES, INC. (US) 1990-06-13 EP claimed
EP-0294940-A1 Pharmaceutical compositions FISONS plc (GB) 1988-12-14 EP claimed
EP-0239798-A1 New pharmaceutical compositions for inhalation CHIESI FARMACEUTICI S.p.A. (IT) 1987-10-07 EP claimed