Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095508 | 0.80 | CES1 (0.55) | CES1CES2AKR1B1TSHRMEN1 | |
| SCHEMBL2241627 | 0.80 | CES1 (0.55) | CES1CES2AKR1B1TSHRMEN1 | |
| SCHEMBL822099 | 0.80 | CES1 (0.55) | CES1CES2AKR1B1TSHRMEN1 | |
| Ammonia Solution, Strong SCHEMBL27465072 | 0.78 | CES1 (0.52) | CES1CES2AKR1B1TSHRMEN1 | |
| SCHEMBL1333665 | 0.78 | CES1 (0.52) | CES1CES2AKR1B1TSHRMEN1 | |
| SCHEMBL6077860 | 0.78 | CES1 (0.52) | CES1CES2AKR1B1TSHRMEN1 | |
| Ammonia Solution, Strong SCHEMBL574785 | 0.78 | CES1 (0.52) | CES1CES2AKR1B1TSHRMEN1 | |
| SCHEMBL5576670 | 0.76 | CES1 (0.50) | CES1CES2AKR1B1TSHRMEN1 | |
| SCHEMBL2338867 | 0.76 | CES1 (0.50) | CES1CES2AKR1B1TSHRMEN1 | |
| SCHEMBL531194 | 0.76 | CES1 (0.50) | CES1CES2AKR1B1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543175-B | Triaryl [1,2,4] triazole [1,5-a] pyridine derivate and preparation method thereof | 上海大学 | 2018-06-01 | — | — | CN | disclosed |
| CN-106543175-A | Triaryl [1,2,4] triazole [1,5 a] pyridine derivate and preparation method thereof | 上海大学 | 2017-03-29 | — | — | CN | disclosed |
| CN-101657414-A | Oxime compound, photosensitive composition, color filter, method for production of the color filter, and liquid crystal display element | FUJIFILM CORP JP | 2010-02-24 | — | — | CN | disclosed |
| EP-2116527-A1 | OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, METHOD FOR PRODUCTION OF THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT | FUJIFILM Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-20030129504-A1 | Photosensitive resin compositon, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof | FUJI PHOTO FILM CO., LTD. | 2003-07-10 | — | — | US | disclosed |
| CN-1022105-C | Process for preparing dihydro benzothiophene | SCHELING CO (US) | 1993-09-15 | — | — | CN | disclosed |
| EP-0212428-B1 | DIHYDROBENZO/B /THIOPHENES AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL AS ANTIFUNGALS | SCHERING CORPORATION (US) | 1990-06-06 | — | — | EP | disclosed |
| US-4731364-A | Dihydrobenzo(B)thiophenes and pharmaceutical compositions thereof useful as antifungals | SCHERING CORPORATION (US) | 1988-03-15 | — | — | US | disclosed |
| CN-86105964-A | Dihydrobenzo [ b ] thiophenes and formulations thereof for use as antifungal agents | — | 1987-03-11 | — | — | CN | disclosed |
| EP-0212428-A1 | Dihydrobenzo/b /thiophenes and pharmaceutical compositions thereof useful as antifungals | SCHERING CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |