Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535057 | 0.87 | ACACB (0.34) | ACACBACACA | |
| SCHEMBL2360849 | 0.87 | ACACB (0.34) | ACACBACACA | |
| SCHEMBL3856569 | 0.87 | ACACB (0.34) | ACACBACACA | |
| SCHEMBL3859694 | 0.83 | ACACB (0.40) | ACACBACACA | |
| SCHEMBL3793047 | 0.83 | ACACB (0.51) | ACACBACACA | |
| SCHEMBL1444711 | 0.83 | ACACB (0.51) | ACACBACACA | |
| SCHEMBL3856244 | 0.82 | ACACB (0.36) | ACACBACACA | |
| SCHEMBL3862469 | 0.82 | ACACB (0.36) | ACACBACACA | |
| SCHEMBL3858163 | 0.81 | ACACB (0.36) | ACACBACACA | |
| SCHEMBL3856567 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111406-A1 | SUBSTITUTED SPIROCHROMANONE DERIVATIVES AS ACC INHIBITORS | Merck & Co., Inc. (US) | 2009-10-28 | — | — | EP | claimed |
| WO-2008088688-A1 | SUBSTITUTED SPIROCHROMANONE DERIVATIVES AS ACC INHIBITORS | MERCK & CO., INC. (US) | 2008-07-24 | — | — | WO | claimed |