Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3856698 | 0.98 | NPSR1 (0.42) | NPSR1CYP4F2CYP4A11LMNAMAPT | |
| SCHEMBL1435555 | 0.74 | NPSR1 (0.47) | NPSR1CYP4F2CYP4A11LMNAMAPT | |
| SCHEMBL1435953 | 0.71 | NPSR1 (0.44) | NPSR1CYP4F2CYP4A11LMNAMAPT | |
| SCHEMBL1434977 | 0.70 | NPSR1 (0.42) | NPSR1CYP4F2CYP4A11LMNAMAPT | |
| SCHEMBL1434486 | 0.69 | NPSR1 (0.42) | NPSR1CYP4F2CYP4A11LMNAMAPT | |
| Hydrochloric Acid SCHEMBL1435952 | 0.69 | NPSR1 (0.42) | NPSR1CYP4F2CYP4A11LMNAMAPT | |
| SCHEMBL1606853 | 0.69 | NPSR1 (0.50) | NPSR1CYP4F2CYP4A11LMNAMAPT | |
| SCHEMBL759802 | 0.67 | NPSR1 (0.54) | NPSR1CYP4F2CYP4A11LMNAMAPT | |
| SCHEMBL20740435 | 0.67 | NPSR1 (0.48) | NPSR1CYP4F2CYP4A11LMNAMAPT | |
| SCHEMBL1604408 | 0.67 | NPSR1 (0.48) | NPSR1CYP4F2CYP4A11LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684787-A4 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1684787-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005051410-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-09 | — | — | WO | disclosed |