⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385704 | 0.81 | — | — | |
| SCHEMBL384100 | 0.79 | — | — | |
| SCHEMBL386282 | 0.77 | — | — | |
| SCHEMBL8391823 | 0.73 | — | — | |
| SCHEMBL386876 | 0.71 | — | — | |
| SCHEMBL383945 | 0.71 | — | — | |
| SCHEMBL386153 | 0.71 | — | — | |
| SCHEMBL5150470 | 0.69 | — | — | |
| SCHEMBL14907 | 0.67 | — | — | |
| SCHEMBL6141371 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050547-A1 | MITOCHONDRIAL COMPLEX I INHIBITORS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-03-18 | — | — | WO | disclosed |
| US-8101650-B2 | Method for treating a immunology-related disease | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8067396-B2 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20100035842-A1 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20090326038-A1 | Method for treating a immunology-related disease | SANKYO COMPANY, LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-7638551-B2 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2009-12-29 | — | — | US | disclosed |
| EP-1471054-B1 | AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE | DAIICHI SANKYO CO LTD (JP) | 2009-07-01 | — | — | EP | disclosed |
| US-20070142335-A1 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2007-06-21 | — | — | US | disclosed |
| US-20070105933-A1 | Amino alcohol compounds | SANKYO COMPANY, LIMITED (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1300405-B1 | AMINO ALCOHOL DERIVATIVES | SANKYO CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-5965611-A | TREATING CHRONIC PERIPHERAL ARTERIAL OCCLUSION BY ADMINISTERING EMULSION COMPRISING ISOCARBACYCLIN, VEGETABLE OIL, PHOSPHOLIPID, AND WATER | TEIGIN LIMITED (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0634171-B1 | PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS | TEIJIN LTD (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5656663-A | THERAPY FOR SKIN ULCERS | TEIJIN LIMITED (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0761225-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING PERIPHERAL CIRCULATION DISORDER | TEIJIN LIMITED (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-5610182-A | ADMINISTERING AN ISOCARBACYCLIN OF SPECIFIC STRUCTURE IN THE FORM OF A FAT EMULSION | TEIJIN, LIMITED (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5530027-A | PROSTAGLANDINS AND/OR ITS OPTICAL ISOMER FOR SKIN DISORDERS | TEIJIN LIMITED (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0693284-A1 | PROSTACYCLIN-CONTAINING OLEAGINOUS OINTMENT | TEIJIN LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |
| EP-0638312-A1 | DERMATOLOGIC PREPARATION COMPOSITION CONTAINING ISOCARBACYCLIN AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0634172-A1 | DERMATOLOGIC PREPARATION COMPOSITION CONTAINING PROSTACYCLIN AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0634171-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS | TEIJIN LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |