SCHEMBL3857337

SCHEMBL3857337

CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(CC(C)C)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 4/20 0.51
KMT2A Q03164 1/20 0.49
SLC6A2 P23975 1/20 0.47
CTSB P07858 1/20 0.47
NTSR2 O95665 10/20 0.46
NTSR1 P30989 10/20 0.46
SORT1 Q99523 6/20 0.46
REN P00797 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3857343 1.00 CAPN1 (0.51) CAPN1KMT2ASLC6A2CTSBNTSR2
SCHEMBL29351166 0.98 KMT2A (0.51) CAPN1KMT2ASLC6A2CTSBNTSR2
SCHEMBL3857550 0.95 CAPN1 (0.55) CAPN1KMT2ASLC6A2CTSBNTSR2
SCHEMBL3857546 0.95 CAPN1 (0.55) CAPN1KMT2ASLC6A2CTSBNTSR2
SCHEMBL29352557 0.94 CAPN1 (0.50) CAPN1KMT2ASLC6A2NTSR2NTSR1
SCHEMBL32681284 0.93 CAPN1 (0.53) CAPN1KMT2ASLC6A2CTSBNTSR2
SCHEMBL29722113 0.92 CAPN1 (0.54) CAPN1KMT2ASLC6A2CTSBNTSR2
SCHEMBL30072960 0.91 CAPN1 (0.48) CAPN1CTSBNTSR2NTSR1SORT1
SCHEMBL31070378 0.90 CAPN1 (0.56) CAPN1KMT2ACTSBNTSR2NTSR1
SCHEMBL31070369 0.90 CAPN1 (0.56) CAPN1KMT2ACTSBNTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040259795-A1 Induction of antibiotic proteins and peptides by LAIT/sCD14-protein GEMMA BIOTECHNOLOGY LTD. (CA) 2004-12-23 US claimed
CN-1322214-A Induction of avidin and of Antibioticpeptide Using LAIT/sCD 14-protein GEMMA BIOTECHNOLOGY LTD (CA) 2001-11-14 CN claimed
EP-1080111-B1 THE INDUCTION OF ANTIOBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN GEMMA BIOTECHNOLOGY LTD (CA) 2012-07-25 EP disclosed
EP-1080111-B1 THE INDUCTION OF ANTIOBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN GEMMA BIOTECHNOLOGY LTD (CA) 2012-07-25 EP disclosed
US-7592310-B2 Induction of antibiotic proteins and peptides by LAIT/sCD14-protein GEMMA BIOTECHNOLOGY LTD. (CA) 2009-09-22 US disclosed
US-7592310-B2 Induction of antibiotic proteins and peptides by LAIT/sCD14-protein GEMMA BIOTECHNOLOGY LTD. (CA) 2009-09-22 US disclosed
US-20040259795-A1 Induction of antibiotic proteins and peptides by LAIT/sCD14-protein GEMMA BIOTECHNOLOGY LTD. (CA) 2004-12-23 US disclosed
US-20040259795-A1 Induction of antibiotic proteins and peptides by LAIT/sCD14-protein GEMMA BIOTECHNOLOGY LTD. (CA) 2004-12-23 US disclosed
CN-1322214-A Induction of avidin and of Antibioticpeptide Using LAIT/sCD 14-protein GEMMA BIOTECHNOLOGY LTD (CA) 2001-11-14 CN disclosed
EP-1080111-A2 THE INDUCTION OF ANTIOBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN Gemma Biotechnology Ltd. (CA) 2001-03-07 EP disclosed
EP-1080111-A2 THE INDUCTION OF ANTIOBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN Gemma Biotechnology Ltd. (CA) 2001-03-07 EP disclosed
WO-1999061468-A3 THE INDUCTION OF ANTIBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN GEMMA BIOTECHNOLOGY LTD (CA) 2000-04-06 WO disclosed
WO-1999061468-A2 THE INDUCTION OF ANTIBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN GEMMA BIOTECHNOLOGY LTD. (CA) 1999-12-02 WO disclosed
WO-1999061468-A2 THE INDUCTION OF ANTIBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN GEMMA BIOTECHNOLOGY LTD. (CA) 1999-12-02 WO disclosed