Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754975 | 0.88 | SERPINE1 (1.00) | SERPINE1 | |
| Tiplasinin SCHEMBL29448190 | 0.85 | SERPINE1 (1.00) | SERPINE1ICMT | |
| Tiplasinin SCHEMBL3052065 | 0.85 | SERPINE1 (1.00) | SERPINE1ICMT | |
| SCHEMBL4938598 | 0.85 | SERPINE1 (0.71) | SERPINE1ICMT | |
| SCHEMBL4936670 | 0.81 | SERPINE1 (1.00) | SERPINE1ICMT | |
| SCHEMBL3856116 | 0.78 | SERPINE1 (0.76) | SERPINE1ICMT | |
| SCHEMBL26073737 | 0.78 | SERPINE1 (0.85) | SERPINE1ICMT | |
| SCHEMBL3858076 | 0.78 | SERPINE1 (0.85) | SERPINE1ICMT | |
| SCHEMBL3857510 | 0.78 | SERPINE1 (1.00) | SERPINE1ICMT | |
| SCHEMBL4752947 | 0.77 | SERPINE1 (1.00) | SERPINE1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010171-A2 | INHIBITORS OF PAI-1 FOR TREATMENT OF MUSCULAR CONDITIONS | Wyeth a Corporation of the State of Delaware (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007098278-A2 | INHIBITORS OF PAI-1 FOR TREATMENT OF MUSCULAR CONDITIONS | WYETH (US) | 2007-08-30 | — | — | WO | disclosed |