Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | MIF | P14174 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19688877 | 0.82 | EGFR (0.37) | PDE5AMIFPDE4BPDE3AMEN1 | |
| SCHEMBL1231181 | 0.81 | EGFR (0.40) | MIFMEN1ALDH1A1KMT2AEGFR | |
| SCHEMBL16078200 | 0.81 | EGFR (0.40) | MIFALDH1A1CYP1A2CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL17849041 | 0.81 | EGFR (0.36) | PDE5AMIFPDE4BPDE3AMEN1 | |
| Hydrochloric Acid SCHEMBL1840928 | 0.80 | EGFR (0.39) | MIFMEN1ALDH1A1KMT2AEGFR | |
| SCHEMBL19688875 | 0.80 | EGFR (0.39) | PDE5AMIFPDE4BPDE3AMEN1 | |
| Hydrochloric Acid SCHEMBL1151493 | 0.80 | EGFR (0.39) | MIFMEN1ALDH1A1KMT2AEGFR | |
| SCHEMBL1844081 | 0.80 | BCHE (0.40) | PDE5AMIFPDE4BPDE3AMEN1 | |
| Hydrochloric Acid SCHEMBL21173665 | 0.79 | EGFR (0.38) | MIFALDH1A1ADORA1EGFRJAK2 | |
| Hydrochloric Acid SCHEMBL17849031 | 0.79 | EGFR (0.38) | PDE5AMIFPDE4BPDE3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7578856-B2 | Dyeing compositions comprising at least one aminopyrazolopyridine oxidation base, at least one coupler and at least one C4-C30 polyol and methods and use thereof | L'OREAL S.A. (FR) | 2009-08-25 | — | — | US | disclosed |