SCHEMBL38602

SCHEMBL38602

Brc1ccc2[nH]c3ccc(Br)cc3c2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHUK O15111 1/20 0.64
AR P10275 1/20 0.57
LMNA P02545 2/20 0.55
HPGD P15428 1/20 0.55
MAPT P10636 2/20 0.53
PIM3 Q86V86 2/20 0.53
JAK2 O60674 2/20 0.52
PIM1 P11309 2/20 0.52
CHEK1 O14757 1/20 0.52
AURKA O14965 1/20 0.52
DAPK3 O43293 1/20 0.52
PRKD3 O94806 1/20 0.52
MAP4K4 O95819 1/20 0.52
PAK4 O96013 1/20 0.52
ABL1 P00519 1/20 0.52
NTRK1 P04629 1/20 0.52
CSF1R P07333 1/20 0.52
RET P07949 1/20 0.52
MET P08581 1/20 0.52
PDGFRB P09619 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366993 1.00 CHUK (0.64) CHUKARLMNAHPGDMAPT
SCHEMBL28288154 0.97 CHUK (0.62) CHUKARLMNAHPGDMAPT
SCHEMBL18830699 0.95 CHUK (0.60) CHUKARLMNAHPGDMAPT
Benzene SCHEMBL28486603 0.95 CHUK (0.60) CHUKARLMNAHPGDMAPT
SCHEMBL3461775 0.93 CHUK (0.58) CHUKARLMNAHPGDMAPT
SCHEMBL18381827 0.91 AR (0.59) CHUKARLMNAHPGDMAPT
SCHEMBL29764121 0.91 CHUK (0.61) CHUKARLMNAHPGDMAPT
SCHEMBL16552984 0.91 CHUK (0.61) CHUKARLMNAHPGDMAPT
SCHEMBL15962698 0.91 CHUK (0.56) CHUKARLMNAHPGDMAPT
SCHEMBL30388549 0.89 AHR (0.64) CHUKARHPGDMAPTGSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2040 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528831-B1 Layered metal-organic framework material and preparation method and use thereof BEIJING UNIVERSITY OF TECHNOLOGY (CN) 2026-01-20 US claimed
CN-118987274-A Preparation method of organic phosphorescence nano scintillator and application of organic phosphorescence nano scintillator in liver cancer treatment 中国人民解放军海军军医大学第三附属医院 2024-11-22 CN claimed
CN-118303347-A Method for testing toxicity of polyhalocarbazole as environmental pollutant by using zebra fish 浙江工业大学 2024-07-09 CN claimed
CN-118243812-A Method for measuring carbazole compounds in aquatic products based on internal standard method 舟山市食品药品检验检测研究院(国家海洋食品质量监督检验中心、浙江省海洋水产品质量检测中心、舟山市医疗器械质量监督检验所、舟山市药品不良反应监测中心、舟山市渔业检验检测中心、舟山市农产品质量检测中心) 2024-06-25 CN claimed
CN-116425764-B Triazine and carbazole-containing heat-activated delayed fluorescence macrocyclic molecule and preparation method and application thereof 上海大学 2024-05-31 CN claimed
CN-117092262-B Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2024-05-28 CN claimed
CN-118047753-A Pyrrolecarboxyl carbazole derivatives and their use in phosphorescent materials 三峡大学 2024-05-17 CN claimed
CN-116688418-B Method for degrading 3, 6-dibromocarbazole by adopting streptomyces 桂林理工大学 2024-05-17 CN claimed
CN-118005557-A Wide-band gap organic luminescent material and preparation method and application thereof 青岛科技大学 2024-05-10 CN claimed
CN-114354790-B Method for detecting 7 halogenated carbazole compounds in aquatic product 舟山市食品药品检验检测研究院 2024-05-10 CN claimed
CN-101343352-B Polymer containing selenium heterocyclic compound and application in preparing luminescent material UNIV SOUTH CHINA TECH 2011-08-17 CN claimed
US-20110152558-A1 PROCESS FOR PRODUCING DIARYL CARBONATES CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) 2011-06-23 US claimed
CN-101318926-B Preparation method of soluble functional carbazole derivant UNIV SOUTH CHINA TECH 2010-12-08 CN claimed
CN-101531627-A N-alkyl substituted carbazole derivative and preparation method thereof UNIV NORTH CHINA 2009-09-16 CN claimed
CN-101318926-A Soluble functional carbazole derivant, preparation method and application thereof UNIV SOUTH CHINA TECH (CN) 2008-12-10 CN claimed
CN-101260296-A Blue luminous polymer and preparation method thereof HUAIHAI INST TECHNOLOGY (CN) 2008-09-10 CN claimed
US-6525043-B2 Bicyclic or tricyclic ketones, oximes, amine oxides or amines are used as calcium or potassium channel modulators NEUROSEARCH A/S (DK) 2003-02-25 US claimed
US-20020065266-A1 Use of ion channel modulating agents NEUROSEARCH A/S (DK) 2002-05-30 US claimed
EP-1187610-A2 USE OF ION CHANNEL MODULATING AGENTS NEUROSEARCH A/S (DK) 2002-03-20 EP claimed
WO-2000069794-A2 USE OF CALCIUM-ACTIVATED POTASSIUM CHANNEL-MODULATING AGENTS NEUROSEARCH A/S (DK) 2000-11-23 WO claimed