Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 13/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PPOX | P50336 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3870666 | 0.98 | FFAR1 (0.48) | FFAR1MRGPRX4PTGDR2MEN1TTR | |
| SCHEMBL5277735 | 0.82 | MRGPRX4 (0.51) | FFAR1MRGPRX4MEN1TTRPPOX | |
| SCHEMBL3712182 | 0.80 | MRGPRX4 (0.53) | FFAR1MRGPRX4MEN1TTRPPOX | |
| SCHEMBL5769694 | 0.80 | KDM4E (0.60) | FFAR1MRGPRX4 | |
| SCHEMBL3859301 | 0.79 | KMT2A (0.53) | FFAR1MRGPRX4MEN1TTRKMT2A | |
| SCHEMBL9834893 | 0.78 | PTGDR2 (0.47) | FFAR1MRGPRX4PTGDR2 | |
| Hydrochloric Acid SCHEMBL3869296 | 0.78 | KMT2A (0.51) | FFAR1MRGPRX4MEN1TTRKMT2A | |
| SCHEMBL17356416 | 0.77 | MRGPRX4 (0.52) | FFAR1MRGPRX4 | |
| SCHEMBL3857991 | 0.76 | KMT2A (0.44) | MEN1KMT2ATDP1 | |
| SCHEMBL17356454 | 0.76 | MRGPRX4 (0.51) | FFAR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592373-B2 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-22 | — | — | US | disclosed |
| US-20050267093-A1 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267093-A1 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | MCHR1, MC4R, MCHR2 | FFAR1 665/4885MRGPRX4 30/4885PTGDR2 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.