⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL1953045 | 0.97 | — | — | |
| SCHEMBL2701063 | 0.79 | — | — | |
| SCHEMBL28196439 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL7600849 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL28200976 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL11845854 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL11760790 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL4202340 | 0.77 | — | — | |
| SCHEMBL28191303 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL27418869 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3370064-A1 | REAGENT AND METHOD FOR MEASURING THROMBIN-ANTITHROMBIN COMPLEX | LSI Medience Corporation (JP) | 2018-09-05 | — | — | EP | claimed |
| US-20180238871-A1 | REAGENT AND METHOD FOR MEASURING THROMBIN-ANTITHROMBIN COMPLEX | PHC CORPORATION (JP) | 2018-08-23 | — | — | US | claimed |
| US-11378577-B2 | Reagent and method for measuring thrombin-antithrombin complex | LSI MEDIENCE CORPORATION (JP) | 2022-07-05 | — | — | US | disclosed |
| US-11378577-B2 | Reagent and method for measuring thrombin-antithrombin complex | LSI MEDIENCE CORPORATION (JP) | 2022-07-05 | — | — | US | disclosed |
| CN-113966220-A | Treatment of TLR-4 mediated diseases and conditions with aptamers targeting TLR-4 | 奥普塔目标公司 | 2022-01-21 | — | — | CN | disclosed |
| US-20200392289-A1 | Biodegradable Polymer and Use Thereof | FULGENT GENETICS, INC. | 2020-12-17 | — | — | US | disclosed |
| WO-2020102382-A1 | TLR9-TARGETED THERAPEUTICS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| US-20190170758-A1 | METHOD OF DETECTION WITH A FLUORESCENT LABELING PARTICLE | FURUKAWA ELECTRIC CO., LTD. (JP) | 2019-06-06 | — | — | US | disclosed |
| US-10203326-B2 | Method of detecting target substance | FURUKAWA ELECTRIC CO., LTD. (JP) | 2019-02-12 | — | — | US | disclosed |
| US-20190011442-A1 | METHOD FOR DETECTING SUBSTANCE OF INTEREST, METHOD FOR QUANTIFYING SUBSTANCE OF INTEREST, KIT, AND METHOD FOR PREPARING REAGENT | FURUKAWA ELECTRIC CO., LTD. (JP) | 2019-01-10 | — | — | US | disclosed |
| US-20180348228-A1 | Method of Determining Quantity of Objects to be Detected in Specimen | ORTHO CLINICAL DIAGNOSTICS KK (JP) | 2018-12-06 | — | — | US | disclosed |
| EP-1100510-A2 | COMBINED PREPARATION OF ANTI-INFECTIOUSLY ACTIVE COMPOUNDS WHICH INHIBIT THE 2-C-METHYLERYTHROSE-4 METABOLIC PATHWAY, AND INHIBITORS OF LIPID METABOLISM | Jomaa, Hassan (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-1999066875-A2 | COMBINED PREPARATION OF ANTI-INFECTIOUSLY ACTIVE COMPOUNDS WHICH INHIBIT THE 2-C-METHYLERYTHROSE-4 METABOLIC PATHWAY, AND INHIBITORS OF LIPID METABOLISM | JOMAA HASSAN (DE) | 1999-12-29 | — | — | WO | disclosed |
| US-5009880-A | Mixture of an anionic and cationic polymer for shampoos, skin lotions, nail strengtheners and hair dyeing; improved fixing and anchoring; smoothness; gloss | L'OREAL (FR) | 1991-04-23 | — | — | US | disclosed |
| US-4719099-A | ANIONIC AND CATIONIC | L'OREAL (FR) | 1988-01-12 | — | — | US | disclosed |
| US-4578195-A | Process for the purification of effluents and purge streams containing trace elements | OLIN CORPORATION (US) | 1986-03-25 | — | — | US | disclosed |
| US-4518760-A | FROM A POLYIMINE AND A POLYISOCYANATE THROUGH A POLYAMINEPOLYUREA INTERMEDIATE, REACTED WITH AMMONIUM HYDROXIDE AND CARBON DISULFIDE | OLIN CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |
| US-4445521-A | ANIONIC AND CATIONIC POLYMER COMBINATION | L'OREAL (FR) | 1984-05-01 | — | — | US | disclosed |
| US-4374102-A | POLY-N, N-DI/DIMETHYLAMINOMETHYL/ACRYLAMIDE; COAGULATION USING A CATIONIC POLYMER | NALCO CHEMICAL COMPANY (US) | 1983-02-15 | — | — | US | disclosed |
| US-4240450-A | HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS | L'OREAL (FR) | 1980-12-23 | — | — | US | disclosed |