Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 19/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 19/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | RXRA | P19793 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1407625 | 0.87 | NR1H3 (0.65) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL3861183 | 0.84 | NR1H2 (0.57) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1407476 | 0.83 | NR1H2 (0.60) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL3866799 | 0.81 | NR1H3 (0.63) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1408160 | 0.79 | NR1H2 (0.66) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1407687 | 0.78 | NR1H2 (0.65) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1407926 | 0.78 | NR1H2 (0.90) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1407787 | 0.77 | NR1H3 (0.60) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1407829 | 0.77 | NR1H2 (0.85) | NR1H2NR1H3NR1I2NR3C1AR | |
| Lxr-623 SCHEMBL29377439 | 0.77 | NR1H2 (1.00) | NR1H2NR1H3NR1I2NR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592363-B2 | Indazoles | WYETH (US) | 2009-09-22 | — | — | US | claimed |