SCHEMBL386154

SCHEMBL386154

COC1[CH]C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3672680 0.72
SCHEMBL1930314 0.72
SCHEMBL10983577 0.68
SCHEMBL10673983 0.68
SCHEMBL10986614 0.68
SCHEMBL7249928 0.67
SCHEMBL16922203 0.64
SCHEMBL14760806 0.64
SCHEMBL2043277 0.64
SCHEMBL2538119 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019736-A Molecular gel compound designed based on cereblon protein and application thereof 标新生物医药科技(上海)有限公司 2024-05-10 CN claimed
CN-117813077-A Composition and method for producing the same 西姆莱斯股份公司 2024-04-02 CN claimed
WO-2024051766-A1 MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-03-14 WO claimed
CN-111606883-B Sulfur-containing compound based on glutarimide skeleton and application thereof 上海科技大学 2023-05-09 CN claimed
CN-114555594-A Substituted azaheterocycles as TRMP8 modulators 奇华顿股份有限公司 2022-05-27 CN claimed
US-20220143002-A1 SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF SHANGHAITECH UNIVERSITY (CN) 2022-05-12 US claimed
EP-3932922-A1 SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF ShanghaiTech University (CN) 2022-01-05 EP claimed
CN-111606883-A Sulfur-containing compound based on glutarimide framework and application thereof 上海科技大学 2020-09-01 CN claimed
EP-3652174-A1 TAM KINASE INHIBITORS Syros Pharmaceuticals, Inc. (US) 2020-05-20 EP claimed
WO-2019014513-A1 TAM KINASE INHIBITORS SYROS PHARMACEUTICALS, INC. (US) 2019-01-17 WO claimed
US-20180020662-A1 Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-25 US claimed
CN-107531635-A Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-yl sulfonamides or salts thereof and their use for enhancing stress tolerance in plants 拜耳作物科学股份公司 2018-01-02 CN claimed
EP-3256448-A1 SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS Bayer CropScience Aktiengesellschaft (DE) 2017-12-20 EP claimed
EP-3210469-A1 USE OF SUBSTITUTED THIO-1,2,4-TRIAZOLES FOR INCREASING STRESS TOLERANCE IN PLANTS Bayer Cropscience AG (DE) 2017-08-30 EP claimed
WO-2016128365-A1 SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-08-18 WO claimed
WO-1996036604-A1 4-ARYLCYCLOHEPTA[c]PYRROLE ANALGESICS ORTHO PHARMACEUTICAL CORPORATION (US) 1996-11-21 WO claimed
WO-1996036605-A1 4-ARYLCYCLOPENTA[c]PYRROLE ANALGESICS ORTHO PHARMACEUTICAL CORPORATION (US) 1996-11-21 WO claimed
CN-118019736-A Molecular gel compound designed based on cereblon protein and application thereof 标新生物医药科技(上海)有限公司 2024-05-10 CN disclosed
US-4372953-A Tetrazole derivatives, and anti-ulcer composition containing the same OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1983-02-08 US disclosed
EP-0035228-A1 Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1981-09-09 EP disclosed