Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | GAA | P10253 | 7/20 | 0.56 |
| ▸ | MPI | P34949 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3861621 | 1.00 | MAPT (0.56) | MAPTGAAMPIHTTLMNA | |
| Perchlorate SCHEMBL4116875 | 0.96 | MAPT (0.52) | MAPTGAAMPIHTTLMNA | |
| SCHEMBL13964132 | 0.86 | MAPT (0.58) | MAPTGAAMPIHTTLMNA | |
| SCHEMBL3859871 | 0.85 | MAPT (0.59) | MAPTGAAMPIHTTLMNA | |
| SCHEMBL3859873 | 0.85 | MAPT (0.59) | MAPTGAAMPIHTTLMNA | |
| SCHEMBL3932865 | 0.82 | MAPT (0.58) | MAPTGAAMPIHTTLMNA | |
| SCHEMBL3932868 | 0.82 | MAPT (0.58) | MAPTGAAMPIHTTLMNA | |
| SCHEMBL13963965 | 0.82 | MAPT (0.58) | MAPTGAAMPIHTTLMNA | |
| Perchlorate SCHEMBL3863336 | 0.80 | MAPT (0.53) | MAPTGAAMPIHTTLMNA | |
| Perchlorate SCHEMBL3863334 | 0.80 | MAPT (0.53) | MAPTGAAMPIHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582123-B2 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |
| EP-2011787-A1 | Dying composition comprising an azomethin-type compound with a pyrazolinone moiety | L'Oreal (FR) | 2009-01-07 | — | — | EP | disclosed |