⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386576 | 0.91 | — | — | |
| SCHEMBL16892581 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL7462252 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL385794 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL8102175 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL387549 | 0.88 | — | — | |
| SCHEMBL6672534 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL386575 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL5142056 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL386565 | 0.88 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586262-A | Nucleoside analogues and uses thereof | 苏州旺山旺水生物医药有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-110256432-A | Inhibit the polycyclic compound of MNK1 and MNK2 | 诺沃斯达药业有限公司 | 2019-09-20 | — | — | CN | claimed |
| WO-2019154133-A1 | DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 北京赛特明强医药科技有限公司 | 2019-08-15 | — | — | WO | claimed |
| CN-105175349-A | Phenyl substituted triazine compounds adopted as EGFR inhibitor, and applications thereof | NANJING SANHOME PHARMACEUTICAL CO LTD | 2015-12-23 | — | — | CN | claimed |
| CN-104341416-A | Protein tyrosine kinase inhibitor and application thereof | NANJING SANHOME PHARMACEUTICAL CO LTD | 2015-02-11 | — | — | CN | claimed |
| CN-102807868-B | Preparation method of mixed (fluorescein isothiocyanate (FITC)/SiO2-CdTe quantum dots (QDs) )-SiO2 super structure encoding particles | UNIV ZHEJIANG NORMAL | 2014-01-15 | — | — | CN | claimed |
| CN-102807868-A | Preparation method of mixed (fluorescein isothiocyanate (FITC)/SiO2-CdTe quantum dots (QDs) )-SiO2 super structure encoding particles | UNIV ZHEJIANG NORMAL | 2012-12-05 | — | — | CN | claimed |
| CN-102524752-A | Method for extracting volatile components from coprinus comatus | BEIJING POLYTECHNIC | 2012-07-04 | — | — | CN | claimed |
| EP-1511734-B1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2010-06-23 | — | — | EP | claimed |
| US-20100048539-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2010-02-25 | — | — | US | claimed |
| WO-2005013888-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-02-17 | — | — | WO | claimed |
| WO-2004103282-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2004-12-02 | — | — | WO | claimed |
| US-6821965-B1 | IMPORTANT IN DISEASE OR MEDICAL CONDITIONS SUCH AS INFLAMMATION AND IMMUNOREGULATION | ASTERZENECA AB (SE) | 2004-11-23 | — | — | US | claimed |
| WO-2004091547-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC (US) | 2004-10-28 | — | — | WO | claimed |
| WO-2004092164-A1 | CYCLIC AMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATION-RELATED DISORDERS MEDIATED BY BRADYKININ | AMGEN, INC. (US) | 2004-10-28 | — | — | WO | claimed |
| WO-2004092116-A1 | BICYCLIC COMPOUNDS HAVING BRADYKININ RECEPTORS AFFINITY AND PHARMACEUTICAL COMPOSITIONS THEREOF | AMGEN, INC. (US) | 2004-10-28 | — | — | WO | claimed |
| WO-2004032879-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-04-22 | — | — | WO | claimed |
| EP-1102743-A1 | AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS | AstraZeneca AB (SE) | 2001-05-30 | — | — | EP | claimed |
| WO-2000007980-A1 | AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2000-02-17 | — | — | WO | claimed |
| EP-0281731-A2 | 1-Aminomethyl-3-aryl-4-cyano-pyrroles | BAYER AG (DE) | 1988-09-14 | — | — | EP | claimed |