⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162367 | 0.72 | — | — | |
| SCHEMBL532519 | 0.67 | — | — | |
| SCHEMBL2803115 | 0.64 | — | — | |
| SCHEMBL3221127 | 0.64 | TSHR (0.37) | — | |
| SCHEMBL11665896 | 0.61 | TSHR (0.35) | — | |
| SCHEMBL184496 | 0.59 | — | — | |
| SCHEMBL7075808 | 0.59 | — | — | |
| SCHEMBL2984 | 0.59 | — | — | |
| SCHEMBL9407651 | 0.59 | — | — | |
| SCHEMBL641199 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299354-B1 | FACTOR VIIA INHIBITORY (THIO)UREA DERIVATIVES, THEIR PREPARATION AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-07-22 | — | — | EP | disclosed |
| US-20090130085-A1 | Amidino-Compounds for Stabilizing Factor VII Polypeptide Formulations | NOVO NORDISH HEALTHCARE AG (CH) | 2009-05-21 | — | — | US | disclosed |
| US-20090041747-A1 | Compounds for Stabilizing Factor VII Polypeptide Formulations | NOVO NORDISK HEALTH CARE AG (CH) | 2009-02-12 | — | — | US | disclosed |
| US-20080312161-A1 | Compounds For Stabilizing Factor VII Polypeptide Formulations | NOVO NORDISK HEALTH CARE AG (CH) | 2008-12-18 | — | — | US | disclosed |
| EP-1856091-A1 | COMPOUNDS FOR STABILIZING FACTOR VII POLYPEPTIDE FORMULATIONS | Novo Nordisk Health Care AG (CH) | 2007-11-21 | — | — | EP | disclosed |
| EP-1856037-A1 | AMIDINO-COMPOUNDS FOR STABILIZING FACTOR VII POLYPEPTIDE FORMULATIONS | Novo Nordisk Health Care AG (CH) | 2007-11-21 | — | — | EP | disclosed |
| EP-1855722-A2 | COMPOUNDS FOR STABILIZING FACTOR VII POLYPEPTIDE FORMULATIONS | Novo Nordisk Health Care AG (CH) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006089952-A1 | AMIDINO-COMPOUNDS POR STABILIZING FACTOR VII POLYPEPTIDE FORMULATIONS | NOVO NORDISK HEALTH CARE AG (CH) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006089953-A1 | COMPOUNDS FOR STABILIZING FACTOR VII POLYPEPTIDE FORMULATIONS | NOVO NORDISK HEALTH CARE AG (CH) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006089954-A2 | COMPOUNDS FOR STABILIZING FACTOR VII POLYPEPTIDE FORMULATIONS | NOVO NORDISK HEALTH CARE AG (CH) | 2006-08-31 | — | — | WO | disclosed |
| US-6743790-B2 | A UREA OR THIOUREA DERIVATIVES CONTAINING AMIDE GROUP USEFUL AS ANTICOAGULANTS AND ANTIINFLAMMATORY AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-06-01 | — | — | US | disclosed |
| US-20020052417-A1 | Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2002-05-02 | — | — | US | disclosed |