SCHEMBL3863183

SCHEMBL3863183

CC(C)(C)[Si](C)(C)OC1CCCC=CCCC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3863180 1.00 PPM1D (0.32) PPM1D
SCHEMBL3867074 0.96 PPM1D (0.31) PPM1D
SCHEMBL3861017 0.96 PPM1D (0.31) PPM1D
SCHEMBL3867069 0.96 PPM1D (0.31) PPM1D
SCHEMBL3861018 0.96 PPM1D (0.31) PPM1D
SCHEMBL3862362 0.94 CYP19A1 (0.30) PPM1D
SCHEMBL3862365 0.94 CYP19A1 (0.30) PPM1D
SCHEMBL3860694 0.94 CYP19A1 (0.30) PPM1D
SCHEMBL3860695 0.94 CYP19A1 (0.30) PPM1D
SCHEMBL3859833 0.94 PPM1D (0.32) PPM1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1483300-A4 RING EXPANSION OF CYCLIC-OLEFINS BY OLEFIN METATHESIS REACTIONS WITH AN ACYCLIC DIENE CALIFORNIA INST OF TECHN (US) 2009-04-08 EP claimed
US-7034096-B2 Ring-expansion of cyclic olefins metathesis reactions with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-04-25 US claimed
US-6987154-B2 Synthesis of A,B-alternating copolymers by olefin metathesis reactions of cyclic olefins or olefinic polymers with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-01-17 US claimed
EP-1483300-A1 RING EXPANSION OF CYCLIC-OLEFINS BY OLEFIN METATHESIS REACTIONS WITH AN ACYCLIC DIENE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2004-12-08 EP claimed
US-20030236367-A1 Ring-expansion of cyclic olefins by olefin metathesis reactions with an acyclic diene CALIFORNIA INSTITUE OF TECHNOLOGY 2003-12-25 US claimed
US-20030236377-A1 Synthesis of A,B-alternating copolymers by olefin metathesis reactions of cyclic olefins or olefinic polymers with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-12-25 US claimed
WO-2003070779-A1 RING EXPANSION OF CYCLIC-OLEFINS BY OLEFIN METATHESIS REACTIONS WITH AN ACYCLIC DIENE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-08-28 WO claimed
US-20200199041-A1 PROCESSES FOR CONVERTING NAPHTHA TO DISTILLATE PRODUCTS EXXONMOBIL RES & ENG CO (US) 2020-06-25 US disclosed
US-7034096-B2 Ring-expansion of cyclic olefins metathesis reactions with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-04-25 US disclosed
US-6987154-B2 Synthesis of A,B-alternating copolymers by olefin metathesis reactions of cyclic olefins or olefinic polymers with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-01-17 US disclosed
US-20030236377-A1 Synthesis of A,B-alternating copolymers by olefin metathesis reactions of cyclic olefins or olefinic polymers with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200199041-A1 PROCESSES FOR CONVERTING NAPHTHA TO DISTILLATE PRODUCTS NQO1, C5, C9 PPM1D 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.