SCHEMBL3863197

SCHEMBL3863197

COc1cccc([C@H](C)NC(=O)CNC(=O)C(=O)Nc2ccc(C(=N)N)s2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F7 P08709 13/20 0.61
▸ F2 P00734 7/20 0.61
▸ GPR139 Q6DWJ6 3/20 0.50
▸ PRKACA P17612 2/20 0.49
▸ GSK3A P49840 2/20 0.49
▸ GSK3B P49841 2/20 0.49
▸ RPS6KA3 P51812 2/20 0.49
▸ ROCK1 Q13464 2/20 0.49
▸ AURKB Q96GD4 2/20 0.49
▸ CLK4 Q9HAZ1 2/20 0.49
▸ CHEK1 O14757 1/20 0.49
▸ AURKA O14965 1/20 0.49
▸ MAP4K4 O95819 1/20 0.49
▸ GRK5 P34947 1/20 0.49
▸ CSNK1A1 P48729 1/20 0.49
▸ CDK8 P49336 1/20 0.49
▸ PRKX P51817 1/20 0.49
▸ PRKCQ Q04759 1/20 0.49
▸ ACVR1 Q04771 1/20 0.49
▸ MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3871836 1.00 F7 (0.61) F7F2GPR139PRKACAGSK3A
SCHEMBL4956858 0.92 F7 (0.70) F7F2GPR139PRKACAGSK3A
SCHEMBL4961418 0.92 F7 (0.70) F7F2GPR139PRKACAGSK3A
SCHEMBL4956873 0.92 F7 (0.70) F7F2GPR139PRKACAGSK3A
SCHEMBL3862743 0.86 F7 (0.56) F7F2GPR139F10
SCHEMBL13936380 0.86 F7 (0.56) F7F2GPR139F10
SCHEMBL3871293 0.86 F7 (0.56) F7F2GPR139F10
SCHEMBL3863203 0.83 F7 (0.84) F7F2GPR139F10
SCHEMBL4958059 0.77 F7 (0.66) F7F2GPR139F10
SCHEMBL4958048 0.77 F7 (0.66) F7F2GPR139F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090041747-A1 Compounds for Stabilizing Factor VII Polypeptide Formulations NOVO NORDISK HEALTH CARE AG (CH) 2009-02-12 — — US disclosed
US-20090041747-A1 Compounds for Stabilizing Factor VII Polypeptide Formulations NOVO NORDISK HEALTH CARE AG (CH) 2009-02-12 — — US disclosed
US-20090041747-A1 Compounds for Stabilizing Factor VII Polypeptide Formulations NOVO NORDISK HEALTH CARE AG (CH) 2009-02-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090041747-A1 Compounds for Stabilizing Factor VII Polypeptide Formulations F7, F5, F13B F7 1/4885F2 13/4885GPR139 2605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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