Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.35 |
| ▸ | CA2 | P00918 | 8/20 | 0.35 |
| ▸ | CA9 | Q16790 | 7/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22722136 | 0.87 | CA1 (0.40) | CA1CA2CA9GGPS1CA12 | |
| SCHEMBL23542126 | 0.87 | CA1 (0.40) | CA1CA2CA9GGPS1CA12 | |
| SCHEMBL22877813 | 0.87 | CA1 (0.40) | CA1CA2CA9GGPS1CA12 | |
| SCHEMBL24241700 | 0.87 | CA1 (0.40) | CA1CA2CA9GGPS1CA12 | |
| SCHEMBL27941831 | 0.82 | GGPS1 (0.38) | CA1CA2GGPS1FDPS | |
| SCHEMBL27369142 | 0.78 | CA1 (0.36) | CA1CA2CA9CA12CA7 | |
| SCHEMBL23481720 | 0.76 | GGPS1 (0.41) | GGPS1FAAHFDPS | |
| SCHEMBL21316539 | 0.74 | GGPS1 (0.40) | CA2GGPS1FAAHFDPS | |
| SCHEMBL25907572 | 0.74 | CA1 (0.33) | CA1CA2CA9CA12CA7 | |
| SCHEMBL12669288 | 0.74 | GGPS1 (0.40) | GGPS1FAAHFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601726-B2 | Substituted pyrazolo[3,4-d]pyrimidines as p38 MAP kinase inhibitors | ROCHE PALO ALTO LLC (US) | 2009-10-13 | — | — | US | disclosed |