Rimonabant

Rimonabant

SCHEMBL38637

Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CNR1

The experimentally established mechanism targets of Rimonabant. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 known ✓ P21554 9/20 1.00
CNR2 P34972 5/20 1.00
CYP2C9 P11712 2/20 1.00
GPR55 Q9Y2T6 2/20 1.00
ABCC4 O15439 1/20 1.00
MLNR O43193 1/20 1.00
ABCB11 O95342 1/20 1.00
CHRM2 P08172 1/20 1.00
ADORA3 P0DMS8 1/20 1.00
ADRA2B P18089 1/20 1.00
ADRA2C P18825 1/20 1.00
DRD1 P21728 1/20 1.00
TBXA2R P21731 1/20 1.00
SLC6A2 P23975 1/20 1.00
HRH2 P25021 1/20 1.00
HTR2A P28223 1/20 1.00
AGTR1 P30556 1/20 1.00
CCKAR P32238 1/20 1.00
CCKBR P32239 1/20 1.00
MC4R P32245 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rimonabant SCHEMBL29373177 1.00 CNR1 (1.00) CNR1CNR2CYP2C9GPR55ABCC4
Rimonabant SCHEMBL1186698 0.99 CNR1 (1.00) CNR1CNR2CYP2C9GPR55ABCC4
Rimonabant SCHEMBL29835931 0.99 CNR1 (1.00) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL12053639 0.99 CNR1 (0.98) CNR1CNR2CYP2C9GPR55ABCC4
Rimonabant SCHEMBL746112 0.98 CNR1 (0.96) CNR1CNR2CYP2C9GPR55ABCC4
Rimonabant SCHEMBL8742390 0.97 CNR1 (0.94) CNR1CNR2CYP2C9GPR55ABCC4
Rimonabant SCHEMBL8742211 0.96 CNR1 (0.93) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL14397516 0.96 CNR1 (0.92) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL29386088 0.95 CNR1 (1.00) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL1040316 0.95 CNR1 (1.00) CNR1CNR2CYP2C9GPR55ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17028 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115192-A1 PHARMACEUTICAL COMPOSITIONS SHENZHEN PHARMACIN CO LTD (CN) 2026-04-30 US claimed
US-20260102502-A1 CANNABINOID DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY UNIV JOHNS HOPKINS (US) 2026-04-16 US claimed
US-20260097051-A1 CANNABICHROMENE AS A THERAPEUTIC MODALITY FOR COVID-19 AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) 2026-04-09 US claimed
US-20260056214-A1 DIAGNOSING AND TREATING END-STAGE RENAL DISEASE (ESRD) IN OBESE SUBJECTS THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2026-02-26 US claimed
US-12544366-B2 Combination of endocannabinoid and mTOR inhibitors in the treatment of neuroendocrine neoplasms HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2026-02-10 US claimed
EP-4358962-B1 TREATMENT FOR AUTOIMMUNE DISEASES COMPRISING NALTREXONE OR A METABOLITE OR ANALOG THEREOF, A CANNABINOID AND A 5-HT RECEPTOR AGONIST LDN PHARMA LTD (GB) 2026-02-04 EP claimed
US-12510524-B2 Compositions containing cannabinoid analog conjugates and methods of use VYRIPHARM ENTERPRISES, LLC (US) 2025-12-30 US claimed
US-20250367134-A1 PERIPHERALIZATION OF CENTRALLY-ACTING CANNABINOID-1 RECEPTOR ANTAGONISTS BY NANOPARTICLES FOR THE TREATMENT METABOLIC RELATED CONDITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-12-04 US claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
US-20250352559-A1 Transdermal Delivery Composition for Delivery of at least one Glucose Controlling Agent, and Method of Delivering at least one Glucose Controlling Agent SKINVISIBLE PHARMACEUTICALS INC (US) 2025-11-20 US claimed
EP-1221952-A1 USE OF CENTRAL CANNABINOID RECEPTOR ANTAGONIST FOR PREPARING MEDICINES Sanofi-Aventis (FR) 2002-07-17 EP claimed
US-6344474-B1 Use of central cannabinoid receptor antagonists for regulating appetence SANOFI-SYNTHELABO (FR) 2002-02-05 US claimed
WO-2001085092-A2 ANTIDIARRHEAL CANNABINOID CB-1 RECEPTOR ANTAGONIST SANOFI-SYNTHELABO (FR) 2001-11-15 WO claimed
WO-2001058450-A2 USE OF CENTRAL CANNABINOID RECEPTOR ANTAGONIST FOR PREPARING MEDICINES DESIGNED TO FACILITATE SMOKING CESSATION SANOFI-SYNTHELABO (FR) 2001-08-16 WO claimed
EP-0969832-B1 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION OF A N-PIPERIDINO- 3-PYRAZOLECARBOXAMIDE DERIVATIVE, ITS SALTS AND THEIR SOLVATES SANOFI SYNTHELABO (FR) 2001-07-04 EP claimed
WO-2001024798-A1 USE OF CENTRAL CANNABINOID RECEPTOR ANTAGONIST FOR PREPARING MEDICINES SANOFI-SYNTHELABO (FR) 2001-04-12 WO claimed
WO-1998043635-A1 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION OF A N-PIPERIDINO- 3-PYRAZOLECARBOXAMIDE DERIVATIVE, ITS SALTS AND THEIR SOLVATES SANOFI-SYNTHELABO (FR) 1998-10-08 WO claimed
EP-0656354-B1 Substituted N-piperidino 3-pyrazolecarboxamide SANOFI SA (FR) 1997-06-04 EP claimed
US-5624941-A Pyrazole derivatives, method of preparing them and pharmaceutical compositions in which they are present SANOFI (FR) 1997-04-29 US claimed
EP-0656354-A1 Substituted N-piperidino 3-pyrazolecarboxamide SANOFI (FR) 1995-06-07 EP claimed