⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386511 | 1.00 | — | — | |
| SCHEMBL818468 | 0.78 | — | — | |
| SCHEMBL819793 | 0.78 | — | — | |
| SCHEMBL818467 | 0.78 | — | — | |
| SCHEMBL28236107 | 0.71 | — | — | |
| SCHEMBL4665903 | 0.69 | — | — | |
| SCHEMBL4665905 | 0.69 | — | — | |
| SCHEMBL16369047 | 0.69 | TSHR (0.53) | — | |
| SCHEMBL11805832 | 0.69 | — | — | |
| SCHEMBL11805843 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380624-A1 | MULTIVALENT LIGAND CLUSTERS WITH DIAMINE SCAFFOLD FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS | Shanghai Argo Biopharmaceutical Co., Ltd. (CN) | 2024-06-12 | — | — | EP | claimed |
| CN-116916963-A | Multivalent ligand clusters with diamine scaffolds for targeted delivery of therapeutic agents | 上海舶望制药有限公司 | 2023-10-20 | — | — | CN | claimed |
| WO-2023045995-A1 | Multivalent Ligand Clusters with Diamine Scaffold for Targeted Delivery of Therapeutic Agents | SHANGHAI ARGO BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-03-30 | — | — | WO | claimed |
| CN-114206389-A | Multivalent ligand clusters for targeted delivery of therapeutic agents | 有丝分裂疗法有限责任公司 | 2022-03-18 | — | — | CN | claimed |
| EP-3923989-A1 | MULTIVALENT LIGAND CLUSTERS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS | Mitotherapeutix LLC (US) | 2021-12-22 | — | — | EP | claimed |
| WO-2020191183-A1 | MULTIVALENT LIGAND CLUSTERS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS | MITOTHERAPEUTIX LLC (US) | 2020-09-24 | — | — | WO | claimed |
| EP-3484908-A1 | NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM Chemicals Llc (US) | 2019-05-22 | — | — | EP | claimed |
| US-20180016232-A1 | SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES | AM CHEMICALS LLC (US) | 2018-01-18 | — | — | US | claimed |
| WO-2018013999-A1 | NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM CHEMICALS LLC (US) | 2018-01-18 | — | — | WO | claimed |
| US-9714560-B2 | Protected scale inhibitors and methods relating thereto | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-07-25 | — | — | US | claimed |
| US-6103891-A | Method for the synthesis of nucleotide or oligonucleotide phosphoramidites | ISIS PHARMACEUTICALS, INC. (US) | 2000-08-15 | — | — | US | claimed |
| US-6040438-A | Reagent useful for synthesizing sulfurized oligonucleotide analogs | ISIS PHARMACEUTICALS, INC. (US) | 2000-03-21 | — | — | US | claimed |
| EP-0983233-A1 | REAGENT USEFUL FOR SYNTHESIZING SULFURIZED OLIGONUCLEOTIDE ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2000-03-08 | — | — | EP | claimed |
| EP-0948514-A1 | METHOD FOR THE SYNTHESIS OF NUCLEOTIDE OR OLIGONUCLEOTIDE PHOSPHORAMIDITES | ISIS PHARMACEUTICALS, INC. (US) | 1999-10-13 | — | — | EP | claimed |
| EP-0948512-A1 | METHOD OF SYNTHESIZING PHOSPHOROTHIOATE OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1999-10-13 | — | — | EP | claimed |
| US-5955600-A | Method for the synthesis of nucleotide or oligonucleotide phosphoramidites | ISIS PHARMACEUTICALS, INC. (US) | 1999-09-21 | — | — | US | claimed |
| US-5902881-A | Reagent useful for synthesizing sulfurized oligonucleotide analogs | ISIS PHARMACEUTICALS, INC. (US) | 1999-05-11 | — | — | US | claimed |
| WO-1998039290-A1 | REAGENT USEFUL FOR SYNTHESIZING SULFURIZED OLIGONUCLEOTIDE ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-11 | — | — | WO | claimed |
| WO-1998029427-A1 | METHOD OF SYNTHESIZING PHOSPHOROTHIOATE OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1998-07-09 | — | — | WO | claimed |
| WO-1998029429-A1 | METHOD FOR THE SYNTHESIS OF NUCLEOTIDE OR OLIGONUCLEOTIDE PHOSPHORAMIDITES | ISIS PHARMACEUTICALS, INC. (US) | 1998-07-09 | — | — | WO | claimed |