Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 2/20 | 0.42 |
| ▸ | AGER | Q15109 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.36 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3693841 | 0.88 | GRIN2B (0.41) | FASNAGERMTNR1ACCR3NAMPT | |
| SCHEMBL3701259 | 0.85 | FASN (0.42) | FASN | |
| Trifluoroacetic Acid SCHEMBL3700536 | 0.83 | GRIN2B (0.42) | FASNABL1BCR | |
| Trifluoroacetic Acid SCHEMBL3697501 | 0.83 | GRIN2B (0.42) | FASNABL1BCR | |
| Trifluoroacetic Acid SCHEMBL3700540 | 0.83 | GRIN2B (0.42) | FASNABL1BCR | |
| SCHEMBL3701385 | 0.83 | GRIN2B (0.44) | CCR3NAMPT | |
| SCHEMBL3698083 | 0.82 | HTR2A (0.42) | FASNACHEHTR4ACACBACACA | |
| SCHEMBL3696842 | 0.81 | BRAF (0.41) | FASNACHEHTR4BRAFABL1 | |
| SCHEMBL3700861 | 0.80 | FASN (0.42) | FASNAGER | |
| SCHEMBL3697727 | 0.79 | HTR2A (0.43) | FASNGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928442-B1 | COMBINATION OF A HYPNOTIC AGENT AND SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUND AND THERAPEUTIC APPLICATION THEREOF | AVENTIS PHARMA INC (US) | 2009-11-04 | — | — | EP | disclosed |