Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 11/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 11/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22300218 | 0.86 | CHRNB4 (0.50) | CHRNB4CHRNA3HDAC8HDAC7ALDH1A1 | |
| SCHEMBL1429750 | 0.82 | CHRNB4 (0.49) | CHRNB4CHRNA3HDAC8ALDH1A1CYP1A2 | |
| SCHEMBL29420191 | 0.82 | CHRNB4 (0.49) | CHRNB4CHRNA3HDAC8ALDH1A1CYP1A2 | |
| SCHEMBL22097362 | 0.82 | CHRNB4 (0.49) | CHRNB4CHRNA3HDAC8HDAC7ALDH1A1 | |
| SCHEMBL22097422 | 0.79 | NISCH (0.51) | CHRNB4CHRNA3HDAC8ALDH1A1CYP1A2 | |
| SCHEMBL30029405 | 0.79 | CHRNB4 (0.46) | CHRNB4CHRNA3GABRA1GABRA5GABRA3 | |
| Methyl Alcohol SCHEMBL28796119 | 0.78 | CHRNB4 (0.45) | CHRNB4CHRNA3ALDH1A1THRBMAPT | |
| SCHEMBL17353143 | 0.77 | CHRNB4 (0.56) | CHRNB4CHRNA3HDAC8ALDH1A1THRB | |
| SCHEMBL13740749 | 0.76 | CHRNB4 (0.46) | CHRNB4CHRNA3HDAC8HDAC7ALDH1A1 | |
| SCHEMBL29833755 | 0.74 | CHRNB4 (0.52) | CHRNB4CHRNA3ALDH1A1CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010910-A | Biazacycloalkane Menin-MLL protein inhibitor, pharmaceutical composition and application thereof | 赛诺哈勃药业（成都）有限公司 | 2026-05-12 | — | — | CN | disclosed |