SCHEMBL38657707

SCHEMBL38657707

CC(C)(C)OC(=O)Nc1ccc(Br)c(CO)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA9 Q16790 1/20 0.45
CYP17A1 P05093 2/20 0.44
HDAC1 Q13547 4/20 0.41
HDAC3 O15379 3/20 0.41
HDAC6 Q9UBN7 3/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
ALDH1A1 P00352 3/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
GAA P10253 1/20 0.40
BCL2 P10415 1/20 0.40
BECN1 Q14457 1/20 0.40
MAPK14 Q16539 1/20 0.40
PSMB8 P28062 1/20 0.40
NAMPT P43490 1/20 0.40
ACHE P22303 1/20 0.39
BACE1 P56817 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20157848 0.89 CA12 (0.45) CA12CA1CA9CYP17A1HDAC1
SCHEMBL16744644 0.86 SREBF2 (0.46) CA12CA1CA9CYP17A1HDAC1
SCHEMBL10323721 0.86 CA12 (0.43) CA12CA1CA9CYP17A1HDAC1
SCHEMBL3439957 0.83 CA12 (0.45) CA12CA1CA9CYP17A1ALDH1A1
SCHEMBL6078955 0.83 CA12 (0.45) CA12CA1CA9CYP17A1ALDH1A1
SCHEMBL16747601 0.83 MCHR1 (0.41) CA12CA1CA9CYP17A1HDAC1
SCHEMBL10819193 0.83 CA12 (0.41) CA12CA1CA9CYP17A1HDAC1
SCHEMBL509795 0.81 CA12 (0.52) CA12CA1CA9CYP17A1ALDH1A1
SCHEMBL38657922 0.81 CA12 (0.42) CA12CA1CA9CYP17A1HDAC1
SCHEMBL12145454 0.81 CA1 (0.48) CA12CA1CA9CYP17A1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed