⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30986146 | 0.82 | — | — | |
| SCHEMBL4020427 | 0.73 | — | — | |
| SCHEMBL30986156 | 0.73 | USP2 (0.32) | — | |
| SCHEMBL30986155 | 0.68 | NEK2 (0.31) | — | |
| SCHEMBL30986179 | 0.67 | — | — | |
| SCHEMBL30968051 | 0.67 | — | — | |
| SCHEMBL30986164 | 0.67 | — | — | |
| SCHEMBL30986171 | 0.66 | USP2 (0.37) | — | |
| SCHEMBL11119942 | 0.65 | — | — | |
| SCHEMBL22089848 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723754-B1 | IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | claimed |