SCHEMBL38658205

SCHEMBL38658205

CC(C)c1ccc(N2CCCC2C(N)=O)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SYK P43405 2/20 0.43
LMNA P02545 2/20 0.43
POLB P06746 1/20 0.43
F10 P00742 1/20 0.43
AR P10275 1/20 0.42
PIK3CA P42336 3/20 0.41
PIK3CD O00329 1/20 0.41
PIK3CG P48736 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ELANE P08246 2/20 0.41
PIM1 P11309 1/20 0.40
BACE1 P56817 1/20 0.40
MAT2A P31153 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24757495 0.90 AR (0.44) SYKF10ARPIK3CAPIK3CD
SCHEMBL77156 0.84 SYK (0.46) SYKF10ARPIK3CAELANE
SCHEMBL13723813 0.84 SYK (0.46) SYKF10ARPIK3CAELANE
SCHEMBL13284534 0.83 CNR2 (0.49) SYKARELANEPIM1BACE1
SCHEMBL15665092 0.83 CNR2 (0.49) SYKARELANEPIM1BACE1
SCHEMBL9135812 0.83 ELANE (0.47) SYKARKMT2AELANEPIM1
SCHEMBL17294200 0.81 SYK (0.46) SYKF10ARPIK3CAELANE
SCHEMBL13723947 0.80 GFER (0.45) SYKPOLBF10ARPIK3CA
SCHEMBL3047808 0.80 SCN9A (0.49) SYKF10ARALDH1A1KMT2A
SCHEMBL15665470 0.80 ELANE (0.54) SYKPOLBARELANEPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed