SCHEMBL38659552

SCHEMBL38659552

Cc1c(Cl)cc(NC(=O)NCc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)cc1CN

nearest known ligand 0.76

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 17/20 0.76
GSPT1 P15170 12/20 0.76
DDB1 Q16531 2/20 0.76
IKZF3 Q9UKT9 1/20 0.76
CYP2C19 P33261 1/20 0.57
KCNH2 Q12809 1/20 0.57
CSNK1A1 P48729 2/20 0.49
IKZF2 Q9UKS7 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31305167 0.91 CRBN (0.79) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL38659631 0.89 CRBN (0.70) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL62578 0.88 CRBN (0.80) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL38660435 0.88 CRBN (0.70) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL23213502 0.88 CRBN (0.69) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL29716364 0.88 CRBN (0.69) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL61575 0.87 CRBN (1.00) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL29360673 0.87 CRBN (1.00) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL31305135 0.87 CRBN (0.74) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL30313161 0.86 CRBN (0.71) CRBNGSPT1DDB1IKZF3CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098644-A1 TARGETED PROTEIN DEGRADATION AGENT, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 北京森妙生物科技有限公司 2026-05-15 WO disclosed