SCHEMBL38660366

SCHEMBL38660366

O=C(CC1CCN(c2ncnc3[nH]c(-c4ccc5c(c4)OCCO5)cc23)CC1)NO

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KIT P10721 16/20 0.54
ENPP1 P22413 1/20 0.48
CSF1R P07333 2/20 0.46
PEAK1 Q9H792 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38662111 0.94 KIT (0.54) KITENPP1CSF1R
SCHEMBL38661156 0.87 KIT (0.55) KITCSF1RPEAK1
SCHEMBL38660548 0.82 ENPP1 (0.66) KITENPP1
SCHEMBL38660632 0.81 ENPP1 (0.60) KITENPP1
SCHEMBL38661014 0.81 KIT (0.55) KITCSF1R
SCHEMBL38661779 0.79 KIT (0.58) KITENPP1
SCHEMBL38662195 0.79 KIT (0.61) KIT
SCHEMBL38661785 0.79 ENPP1 (0.51) KITENPP1CSF1R
SCHEMBL38660544 0.77 KIT (0.56) KIT
SCHEMBL38662193 0.77 CSF1R (0.51) KITENPP1CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036736-A Pyrrolo [2,3-d ] pyrimidine derivative, synthetic method and application 云南大学 2026-05-15 CN disclosed