Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660474 | 0.79 | PTK2 (0.55) | P4HTMGAAPTK2TDP1L3MBTL1 | |
| SCHEMBL38660185 | 0.78 | BRD4 (0.70) | GAATDP1L3MBTL1BRD4NPC1 | |
| SCHEMBL11549645 | 0.78 | BRD4 (0.70) | GAATDP1L3MBTL1BRD4NPC1 | |
| SCHEMBL38660786 | 0.78 | P4HTM (0.51) | P4HTMGAAPTK2TDP1L3MBTL1 | |
| SCHEMBL38661985 | 0.77 | BRD4 (0.50) | P4HTMGAAPTK2TDP1L3MBTL1 | |
| SCHEMBL11159971 | 0.77 | MAPT (0.49) | TDP1L3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL38660615 | 0.75 | AKR1C3 (0.71) | ALDH1A1KDM4EMAPTTSHRNPSR1 | |
| SCHEMBL38661290 | 0.74 | MEN1 (0.55) | TDP1L3MBTL1BRD4NPC1RAB9A | |
| SCHEMBL12427892 | 0.74 | MAPK1 (0.58) | P4HTMGAAPTK2L3MBTL1AHR | |
| SCHEMBL8970981 | 0.74 | PTK2 (0.70) | P4HTMGAAPTK2AHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036638-A | AKR1C3 inhibitor with tricyclic structure and application thereof | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |