SCHEMBL38662000

SCHEMBL38662000

Cc1cc(C#N)cc(C)c1OC(=O)C1c2ccccc2N(C)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 2/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 1/20 0.36
EGFR P00533 2/20 0.36
SRC P12931 1/20 0.36
POLB P06746 1/20 0.34
MGLL Q99685 3/20 0.33
TSHR P16473 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
BRD4 O60885 1/20 0.31
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38665521 0.86 HDAC4 (0.49) HDAC4HDAC7HDAC5L3MBTL1MEN1
SCHEMBL38664478 0.83 HDAC4 (0.51) HDAC4HDAC7HDAC5L3MBTL1MEN1
SCHEMBL6254107 0.83 HDAC4 (0.51) HDAC4HDAC7HDAC5L3MBTL1MEN1
SCHEMBL38664716 0.78 HDAC4 (0.49) HDAC4HDAC7HDAC5L3MBTL1MEN1
SCHEMBL14564645 0.77 HDAC4 (0.43) HDAC4HDAC7HDAC5L3MBTL1MEN1
SCHEMBL38661832 0.76 HDAC4 (0.45) HDAC4HDAC7HDAC5L3MBTL1MEN1
SCHEMBL7793127 0.76 HDAC4 (0.53) HDAC4HDAC7HDAC5L3MBTL1MEN1
SCHEMBL4192299 0.76 HDAC4 (0.40) HDAC4HDAC7HDAC5L3MBTL1MEN1
SCHEMBL38664713 0.75 HDAC4 (0.46) HDAC4HDAC7HDAC5L3MBTL1MEN1
SCHEMBL7787087 0.75 HDAC4 (0.51) HDAC4HDAC7HDAC5L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099510-A1 RESILIENT MARKER COMPOUNDS MINTON, TREHARNE & DAVIES LIMITED (GB) 2026-05-15 WO disclosed