SCHEMBL38662402

SCHEMBL38662402

CCOC(=O)CNC(=O)/C(C#N)=C/c1ccc(-c2cc(Cl)ccc2Cl)o1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.57
TP53 P04637 6/20 0.57
BLM P54132 1/20 0.57
LMNA P02545 3/20 0.55
POLB P06746 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
KDM4E B2RXH2 2/20 0.54
SIRT2 Q8IXJ6 3/20 0.53
MTOR P42345 1/20 0.53
SIRT1 Q96EB6 1/20 0.53
SIRT3 Q9NTG7 1/20 0.53
THRB P10828 2/20 0.51
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38661672 0.87 MAPT (0.64) MAPTTP53BLMLMNAPOLB
SCHEMBL38661979 0.83 MAPT (0.59) MAPTTP53BLMLMNAPOLB
SCHEMBL38662561 0.83 MAPT (0.61) MAPTTP53BLMLMNAPOLB
SCHEMBL38662282 0.82 MAPT (0.63) MAPTTP53BLMLMNAPOLB
SCHEMBL38661813 0.82 MAPT (0.58) MAPTTP53BLMLMNAPOLB
SCHEMBL38661255 0.82 MAPT (0.56) MAPTTP53BLMLMNAPOLB
SCHEMBL38664665 0.82 MAPT (0.62) MAPTTP53BLMLMNAPOLB
SCHEMBL38661148 0.81 MAPT (0.64) MAPTTP53BLMLMNAPOLB
SCHEMBL38661642 0.81 MAPT (0.59) MAPTTP53BLMLMNAPOLB
SCHEMBL38662248 0.80 MAPT (0.60) MAPTTP53BLMLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101218-A1 NOVEL COMPOUND AND COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR INHIBITING HEPATITIS B VIRUS (HBV) PROLIFERATION 아주대학교 산학협력단 2026-05-15 WO disclosed